Evidence map›Paper›PMID 30061285›Full record

ArticleAntimicrobial agents and chemotherapy2018

Synergistic Activity of Colistin-Containing Combinations against Colistin-Resistant Enterobacteriaceae.

Thea Brennan-Krohn, Alejandro Pironti, James E Kirby

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
5.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 116 citations in OpenAlex.

  1. Biofilm-Mediated Antimicrobial Resistance in PediatricAntibiotics (Basel, Switzerland) · 2026
    Review
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  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
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  11. Prevalence ofAntibiotics (Basel, Switzerland) · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Thea Brennan-KrohnDepartment of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Alejandro PirontiBroad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
James E KirbyDepartment of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA jekirby@bidmc.harvard.edu.
Beth Israel Deaconess Medical Center · USBoston Children's Hospital · USBroad Institute · US

Funding

Antibacterial Resistance Leadership Group (ARLG)UM1AI104681 · NIAID · DUKE UNIVERSITY · PI Vance G. Fowler, Henry F HENRY CHAMBERS · 2013 to 2026
$180.8M
Viral Genomics: evolution, spread, and host interactionsU19AI110818 · NIAID · BROAD INSTITUTE, INC. · PI CUOMO, CHRISTINA A · 2014 to 2024
$66.5M
INFECTIOUS DISEASE AND BASIC MICROBIOLOGICAL MECHANISMST32AI007061 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Marcia B Goldberg · 1985 to 2026
$12.1M
Pediatric Infectious Diseases Research TrainingT32HD055148 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI WESSELS, MICHAEL R · 2008 to 2018
$2.7M
Antimicrobial Synergy for Carbapenem-Resistant Enterobacteriaceae - Administrative SupplementK08AI132716 · NIAID · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BRENNAN-KROHN, THEA · 2018 to 2022
$916k
NIAID NIH HHS K08 AI132716NIAID NIH HHS T32 AI007061NIAID NIH HHS U19 AI110818NIAID NIH HHS UM1 AI104681NICHD NIH HHS T32 HD055148
6 · The paper itself

Abstract

Resistance to colistin, a polypeptide drug used as an agent of last resort for the treatment of infections caused by multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-negative bacteria, including carbapenem-resistant

Indexed as

Anti-Bacterial AgentsAzithromycinColistinDrug Resistance, Multiple, BacterialDrug SynergismEnterobacteriaceaeFusidic AcidLinezolidMicrobial Sensitivity TestsRifampinAnti-Bacterial AgentsAzithromycinColistinFusidic AcidLinezolidRifampincarbapenem-resistant EnterobacteriaceaecheckerboardcolistinCREEnterobacteriaceaeMCR-1NDM-1synergytime-kill curves

Identifiers

PMID30061285
PMCPMC6153801
OpenAlexW2885500619

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.