Evidence map›Paper›PMID 30061196›Full record

ArticleDisease models & mechanisms2018

RERE deficiency leads to decreased expression of GATA4 and the development of ventricular septal defects.

Bum Jun Kim, Hitisha P Zaveri, Valerie K Jordan, Andres Hernandez-Garcia, Daron J Jacob, Diana L Zamora, Wei Yu, Robert J Schwartz, Daryl A Scott

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Disease models & mechanisms, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Bum Jun KimDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
Hitisha P ZaveriDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
Valerie K JordanDepartment of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX 77030, USA.
Andres Hernandez-GarciaDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
Daron J JacobDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-5834-6448
Diana L ZamoraDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-3198-700X
Wei YuDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77004, USA.
Robert J SchwartzDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77004, USA.
Daryl A ScottDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA dscott@bcm.edu.ORCID 0000-0003-1460-5169
Baylor College of Medicine · USUniversity of Houston · US

Funding

The Role of RERE in Congenital Cardiac AnomaliesR03HD075892 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI SCOTT, DARYL ARMSTRONG · 2014 to 2015
$156k
NICHD NIH HHS R03 HD075892
6 · The paper itself

Abstract

Deletions of chromosome 1p36 are associated with a high incidence of congenital heart defects (CHDs). The arginine-glutamic acid dipeptide repeats gene (

Indexed as

Gene Expression Regulation, DevelopmentalAllelesAnimalsCarrier ProteinsCell ProliferationEmbryo, MammalianEndocardial CushionsEndocardiumEpithelial-Mesenchymal TransitionGATA4 Transcription FactorHeart Septal Defects, VentricularMesodermMiceMice, Inbred C57BLMice, KnockoutNerve Tissue Proteinsatrophin 2, mouseCarrier ProteinsGATA4 Transcription FactorNerve Tissue ProteinsRepressor ProteinsAtrioventricular canalAtrioventricular cushionEndothelial-to-mesenchymal transitionGATA4REREVentricular septal defects

Identifiers

PMID30061196
PMCPMC6176990
OpenAlexW2883197460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.