ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018
Reward Learning over Weeks Versus Minutes Increases the Neural Representation of Value in the Human Brain.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- The effects of high versus low frequency of combined physical and cognitive training on cognitive function in older adults with cognitive decline: a quasi-experimental study.BMC geriatrics · 2023Trial
- Post-learning replay of hippocampal-striatal activity is biased by reward-prediction signals.Nature communications · 2025Article
- Dual process impairments in reinforcement learning and working memory systems underlie learning deficits in physiological anxiety.PLoS computational biology · 2025Article
- Stability and robustness of idiosyncratic choice bias.Communications psychology · 2025Article
- A novel free-operant framework enables experimental habit induction in humans.Behavior research methods · 2024Article
- Causal learning with delays up to 21 hours.Psychonomic bulletin & review · 2024Article
- Naturalistic reinforcement learning.Trends in cognitive sciences · 2024Review
- Article
- Functional Organization of Auditory and Reward Systems in Aging.Journal of cognitive neuroscience · 2023Article
- Distinct replay signatures for prospective decision-making and memory preservation.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Anesthesia Resistant Memories in Drosophila, a Working Perspective.International journal of molecular sciences · 2022Review
- Spaced training enhances equine learning performance.Animal cognition · 2022Article
- Macaques fail to develop habit responses during extended training on a reinforcer devaluation task.Behavioral neuroscience · 2022Article
- Mixing memory and desire: How memory reactivation supports deliberative decision-making.Wiley interdisciplinary reviews. Cognitive science · 2022Review
- Reward learning and working memory: Effects of massed versus spaced training and post-learning delay period.Memory & cognition · 2022Article
- Memory consolidation as an adaptive process.Psychonomic bulletin & review · 2021Review
- Minimal impact of consolidation on learned switch-readiness.Journal of experimental psychology. Learning, memory, and cognition · 2021Article
- Reactivation of Single-Episode Pain Patterns in the Hippocampus and Decision Making.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Value network engagement and effects of memory-related processing during encoding and retrieval of value.Brain and cognition · 2021Article
- Retention of Value Representations Across Time in People With Schizophrenia and Healthy Control Subjects.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Over the past few decades, neuroscience research has illuminated the neural mechanisms supporting learning from reward feedback. Learning paradigms are increasingly being extended to study mood and psychiatric disorders as well as addiction. However, one potentially critical characteristic that this research ignores is the effect of time on learning: human feedback learning paradigms are usually conducted in a single rapidly paced session, whereas learning experiences in ecologically relevant circumstances and in animal research are almost always separated by longer periods of time. In our experiments, we examined reward learning in short condensed sessions distributed across weeks versus learning completed in a single "massed" session in male and female participants. As expected, we found that after equal amounts of training, accuracy was matched between the spaced and massed conditions. However, in a 3-week follow-up, we found that participants exhibited significantly greater memory for the value of spaced-trained stimuli. Supporting a role for short-term memory in massed learning, we found a significant positive correlation between initial learning and working memory capacity. Neurally, we found that patterns of activity in the medial temporal lobe and prefrontal cortex showed stronger discrimination of spaced- versus massed-trained reward values. Further, patterns in the striatum discriminated between spaced- and massed-trained stimuli overall. Our results indicate that single-session learning tasks engage partially distinct learning mechanisms from distributed training. Our studies begin to address a large gap in our knowledge of human learning from reinforcement, with potential implications for our understanding of mood disorders and addiction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.