Evidence map›Paper›PMID 30061166›Full record

ArticleDevelopment (Cambridge, England)2018

Myc activity is required for maintenance of the neuromesodermal progenitor signalling network and for segmentation clock gene oscillations in mouse.

Ioanna Mastromina, Laure Verrier, Joana Clara Silva, Kate G Storey, J Kim Dale

Open access · hybridAbstract read
In one paragraph

Article in Development (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Lineage tracing of axial progenitors using Nkx1-2CreERDevelopment (Cambridge, England) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ioanna MastrominaDivision of Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK.
Laure VerrierDivision of Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK.
Joana Clara SilvaDivision of Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK.
Kate G StoreyDivision of Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK.
J Kim DaleDivision of Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK j.k.dale@dundee.ac.uk.ORCID 0000-0002-9294-947X
University of Dundee · GB

Funding

Cancer Research UKWellcome Trust 097945/Z/11/ZWellcome Trust 102817/Z/13/Z
6 · The paper itself

Abstract

The Myc transcriptional regulators are implicated in a range of cellular functions, including proliferation, cell cycle progression, metabolism and pluripotency maintenance. Here, we investigated the expression, regulation and function of the Myc family during mouse embryonic axis elongation and segmentation. Expression of both

Indexed as

AnimalsBiological ClocksBody PatterningCell DifferentiationCLOCK ProteinsDown-RegulationEmbryo, MammalianFemaleFibroblast Growth Factor 8Fibroblast Growth FactorsGene Expression Regulation, DevelopmentalHumansMesodermMiceProto-Oncogene Proteins c-mycRNA, MessengerCLOCK ProteinsFgf8 protein, mouseFibroblast Growth Factor 8Fibroblast Growth FactorsProto-Oncogene Proteins c-mycRNA, MessengerWnt ProteinsEmbryoMycNeuromesodermal progenitorsPresomitic mesodermSegmentation clock

Identifiers

PMID30061166
PMCPMC6078331
OpenAlexW2885369907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.