ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2018
Vibration-induced Behavioral Responses and Response Threshold in Female C57BL/6 Mice.
Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Effects of partial cage dividers on animal welfare and social behavior in California mice (Applied animal behaviour science · 2026Article
- Sonic vibration ameliorates inflammatory diseases via the up-regulation of IL-10.Animal cells and systems · 2024Article
- A Review of the Effects of Some Extrinsic Factors on Mice Used in Research.Comparative medicine · 2023Review
- The rat Lux Actuating Search Task (LAST) and effects of sleep deprivation on task reversal performance.Neurobiology of sleep and circadian rhythms · 2022Article
- Evaluation of Ambient Sound, Vibration, and Light in Rodent Housing Rooms.Journal of the American Association for Laboratory Animal Science : JAALAS · 2022Article
- What's wrong with my experiment?: The impact of hidden variables on neuropsychopharmacology research.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Review
- Noise and Vibration in the Vivarium: Recommendations for Developing a Measurement Plan.Journal of the American Association for Laboratory Animal Science : JAALAS · 2020Article
- Possible challenges in behavioral phenotyping of rodents following COVID-19 lockdown.Lab animal · 2020Article
- Vibration in mice: A review of comparative effects and use in translational research.Animal models and experimental medicine · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite documented adverse effects, limits for rodent exposure to vibration in the laboratory animal facility have not been established. This study used female C57BL/6 mice to determine the frequencies of vibration at which mice were most sensitive to behavioral changes, the highest magnitude of vibration that would not cause behavioral changes, the behavioral changes that occur in response to vibration, and the extent to which mice habituate to vibration. Mice were exposed to frequencies of vibration between 20 and 190 Hz at accelerations of 0.05 to 1.0 m/s2. Behavioral responses were videorecorded and subsequently scored. Mice showed the most behavioral responses at 1.0 m/s2. At intermediate accelerations of 0.5 and 0.75 m/s2, behavioral responses were most prevalent at frequencies of 70 to 100 Hz. In contrast, at an acceleration of 0.05 m/s2, mice did not show any discernible behavioral response. Behavioral responses induced by the initiation of vibration were transient, generally lasting only 2 to 10 s. Behaviors in awake mice included abrupt freezing of motion, hunched posture, and surveying the cage environment. In mice that were asleep, responses consisted of lifting the head suddenly with or without prior shifting of body position. When exposed to multiple periods of vibration over a short time, responses seemed to decrease. In summary, mice were particularly sensitive to vibration between 70 to 100 Hz, did not respond to the slowest acceleration (0.05 m/s2), and exhibited transient responses at the initiation of vibration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.