ReviewVeterinary research2018
Innovative drugs, chemicals, and enzymes within the animal production chain.
Review in Veterinary research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 38 citations in OpenAlex.
- Antimicrobial Activity of Metal-Based Danofloxacin Complexes Against Pathogenic Microorganisms.Molecules (Basel, Switzerland) · 2026Article
- Safe Meat, Smart Science: Biotechnology's Role in Antibiotic Residue Removal.Antibiotics (Basel, Switzerland) · 2025Review
- Feeding laying hens with lactobacilli improves internal egg quality and animal health.World journal of microbiology & biotechnology · 2023Article
- Xylo-oligosaccharides improve the adverse effects of plant-based proteins on weaned piglet health by maintaining the intestinal barrier and inhibiting harmful bacterial growth.Frontiers in microbiology · 2023Article
- Post-weaning diarrhea and use of feedstuffs in pigs.Animal frontiers : the review magazine of animal agriculture · 2022Article
- Review
- Metagenomic insights into the microbial community structure and resistomes of a tropical agricultural soil persistently inundated with pesticide and animal manure use.Folia microbiologica · 2022Article
- Insights in the Development and Uses of Alternatives to Antibiotic Growth Promoters in Poultry and Swine Production.Antibiotics (Basel, Switzerland) · 2022Review
- Pollution by Antibiotics and Antimicrobial Resistance in LiveStock and Poultry Manure in China, and Countermeasures.Antibiotics (Basel, Switzerland) · 2021Review
- Antibiotics and Antibiotic Resistance Genes in Animal Manure - Consequences of Its Application in Agriculture.Frontiers in microbiology · 2021Review
- Nutritional Aspects of Ecologically Relevant Phytochemicals in Ruminant Production.Frontiers in veterinary science · 2021Review
- Dietary Application of Tannins as a Potential Mitigation Strategy for Current Challenges in Poultry Production: A Review.Animals : an open access journal from MDPI · 2020Review
- Alternative Anti-Infective Treatments to Traditional Antibiotherapy against Staphylococcal Veterinary Pathogens.Antibiotics (Basel, Switzerland) · 2020Review
- Evaluation of lipid matrix microencapsulation for intestinal delivery of thymol in weaned pigs.Translational animal science · 2020Article
- Biocide Potentiation Using Cinnamic Phytochemicals and Derivatives.Molecules (Basel, Switzerland) · 2019Article
- Antimicrobial resistance and presence of virulence factor genes in Trueperella pyogenes isolated from pig lungs with pneumonia.Tropical animal health and production · 2019Article
- Effect of Manitoba-Grown Red-Osier Dogwood Extracts on Recovering Caco-2 Cells from HAntioxidants (Basel, Switzerland) · 2019Article
- Distribution and localization of porcine calcium sensing receptor in different tissues of weaned piglets1.Journal of animal science · 2019Article
- Proteomics and Lipidomics of Black Soldier Fly (Diptera: Stratiomyidae) and Blow Fly (Diptera: Calliphoridae) Larvae.Journal of insect science (Online) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The alarming number of recently reported human illnesses with bacterial infections resistant to multiple antibacterial agents has become a serious concern in recent years. This phenomenon is a core challenge for both the medical and animal health communities, since the use of antibiotics has formed the cornerstone of modern medicine for treating bacterial infections. The empirical benefits of using antibiotics to address animal health issues in animal agriculture (using therapeutic doses) and increasing the overall productivity of animals (using sub-therapeutic doses) are well established. The use of antibiotics to enhance profitability margins in the animal production industry is still practiced worldwide. Although many technical and economic reasons gave rise to these practices, the continued emergence of antimicrobial resistant bacteria is furthering the need to reduce the use of medically important antibiotics. This will require improving on-farm management and biosecurity practices, and the development of effective antibiotic alternatives that will reduce the dependence on antibiotics within the animal industry in the foreseeable future. A number of approaches are being closely scrutinized and optimized to achieve this goal, including the development of promising antibiotic alternatives to control bacterial virulence through quorum-sensing disruption, the use of synthetic polymers and nanoparticles, the exploitation of recombinant enzymes/proteins (such as glucose oxidases, alkaline phosphatases and proteases), and the use of phytochemicals. This review explores the most recent approaches within this context and provides a summary of practical mitigation strategies for the extensive use of antibiotics within the animal production chain in addition to several future challenges that need to be addressed.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.