ArticleEnvironmental health : a global access science source2018
Delayed discovery, dissemination, and decisions on intervention in environmental health: a case study on immunotoxicity of perfluorinated alkylate substances.
Article in Environmental health : a global access science source, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- PFAS in the Urban Atmosphere Detected with I‑CIMS and LC-ESI Orbitrap Mass Spectrometer.ACS ES&T air · 2026Article
- Emerging toxicological awareness of per- and polyfluoroalkyl substances: the rising concern over 'forever chemicals'.Disease models & mechanisms · 2025Review
- PFAS biodegradation by Labrys portucalensis F11: Evidence of chain shortening and identification of metabolites of PFOS, 6:2 FTS, and 5:3 FTCA.The Science of the total environment · 2025Article
- Cross-cutting studies of per- and polyfluorinated alkyl substances (PFAS) in Arctic wildlife and humans.The Science of the total environment · 2024Review
- Dioxins vs. PFAS: Science and Policy Challenges.Environmental health perspectives · 2024Article
- Review
- Research Progress of Perfluoroalkyl Substances in Edible Oil-A Review.Foods (Basel, Switzerland) · 2023Review
- Domestic Dogs and Horses as Sentinels of Per- and Polyfluoroalkyl Substance Exposure and Associated Health Biomarkers in Gray's Creek North Carolina.Environmental science & technology · 2023Article
- Centurial Persistence of Forever Chemicals at Military Fire Training Sites.Environmental science & technology · 2023Article
- Birth Outcomes in Relation to Prenatal Exposure to Per- and Polyfluoroalkyl Substances and Stress in the Environmental Influences on Child Health Outcomes (ECHO) Program.Environmental health perspectives · 2023Article
- Modifiable contributing factors to COVID-19: A comprehensive review.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2023Review
- Differences in barriers for controlled learning about safety between biotechnology and chemistry.Nature communications · 2022Article
- Association between serum per- and polyfluoroalkyl substances concentrations and common cold among children and adolescents in the United States.Environment international · 2022Article
- Understanding Public Perceptions of Per- and Polyfluoroalkyl Substances: Infodemiology Study of Social Media.Journal of medical Internet research · 2022Article
- Characterization of Per- and Polyfluorinated Alkyl Substances Present in Commercial Anti-fog Products and TheirEnvironmental science & technology · 2022Article
- Concentrations of tetanus and diphtheria antibodies in vaccinated Greenlandic children aged 7-12 years exposed to marine pollutants, a cross sectional study.Environmental research · 2022Article
- Toolkit for detecting misused epidemiological methods.Environmental health : a global access science source · 2021Article
- Investigating Molecular Mechanisms of Immunotoxicity and the Utility of ToxCast for Immunotoxicity Screening of Chemicals Added to Food.International journal of environmental research and public health · 2021Article
- Reconstructing the Composition of Per- and Polyfluoroalkyl Substances in Contemporary Aqueous Film-Forming Foams.Environmental science & technology letters · 2021Article
- Children's Environmental Health: A Systems Approach for Anticipating Impacts from Chemicals.International journal of environmental research and public health · 2020Review
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Identification and characterization of environmental hazards that impact human health must rely on the best possible science to inform and inspire appropriate public health intervention. The perfluorinated alkylate substances (PFASs) are persistent emerging pollutants that are now being recognized as important human health hazards. Although the PFASs have been produced for over 60 years, academic research on environmental health aspects has appeared only in the most recent 10 years or so. In the meantime, these persistent chemicals accumulated in the global environment. Some early studies e.g., on population exposures and toxicity, were not released to the public until after year 2000. Still, the first PFAS risk assessments ignored these reports and relied on scant journal publications. The first guidelines and legal limits for PFAS exposure, e.g., from drinking water, were proposed 10 years ago. They have decreased substantially since then, but remain higher than suggested by data on human adverse effects, especially on the immune system, that occur at background exposure levels. By now, the best-known PFASs are being phased out, and related PFASs are being introduced as substitutes. Given the substantial delays in discovery of PFAS toxicity, in dissemination of findings, and in regulatory decisions, PFAS substitutes and other persistent industrial chemicals should be subjected to prior scrutiny before widespread usage.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.