ArticleNutrients2018
The Relationship between Single Nucleotide Polymorphisms in Taste Receptor Genes, Taste Function and Dietary Intake in Preschool-Aged Children and Adults in the Guelph Family Health Study.
Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- New insight into human sweet taste: a genome-wide association study of the perception and intake of sweet substances.The American journal of clinical nutrition · 2019Pooled it
- Data-Driven Clustering Approach to Derive Taste Perception Profiles from Sweet, Salt, Sour, Bitter, and Umami Perception Scores: An Illustration among Older Adults with Metabolic Syndrome.The Journal of nutrition · 2021Trial
- Choosing sweeteners wisely-nutrigenetic study on childhood obesity.Nutrition & metabolism · 2025Article
- Associations of TAS1R2 and TAS2R38 Genetic Variants with Sugar-Sweetened Beverage Intake and Obesity Risk in Kuwaiti Adolescents: A Cross-Sectional Study.Children (Basel, Switzerland) · 2025Article
- Article
- Rare variants at KCNJ2 are associated with LDL-cholesterol levels in a cross-population study.NPJ genomic medicine · 2024Article
- Understanding the determinants of sweet taste liking in the African and East Asian ancestry groups in the U.S.-A study protocol.PloS one · 2024Article
- Understanding the Determinants of Sweet Liking in the African and East Asian Ancestry Groups in the U.S. - A Study Protocol.Research square · 2023Article
- Increased WIC Cash Value Benefit is Associated with Greater Amount and Diversity of Redeemed Fruits and Vegetables among Participating Households.Current developments in nutrition · 2023Article
- Dietary Sugar Research in Preschoolers: Methodological, Genetic, and Cardiometabolic Considerations.Reviews in cardiovascular medicine · 2023Review
- Genetic variation in salt taste receptors impact salt intake and blood pressure.Scientific reports · 2023Article
- The impact of excessive salt intake on human health.Nature reviews. Nephrology · 2022Review
- The Influence of Common Noncommunicable Diseases on Chemosensory Perception and Clinical Implications in Children and Adolescents.Advances in nutrition (Bethesda, Md.) · 2022Review
- Landscape of Variability in Chemosensory Genes Associated With Dietary Preferences in Indian Population: Analysis of 1029 Indian Genomes.Frontiers in genetics · 2022Article
- Advances in TRP channel drug discovery: from target validation to clinical studies.Nature reviews. Drug discovery · 2022Review
- Oral Microbiota-Host Interaction Mediated by Taste Receptors.Frontiers in cellular and infection microbiology · 2022Review
- Nutrigenomics reveals potential genetic underpinning of diverse taste preference of Chinese men.Genes & genomics · 2021Article
- Interactions between Chemesthesis and Taste: Role of TRPA1 and TRPV1.International journal of molecular sciences · 2021Review
- Association between Sour Taste SNPNutrients · 2021Article
- Children's Fruit and Vegetable Preferences Are Associated with Their Mothers' and Fathers' Preferences.Foods (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Taste is a fundamental determinant of food selection, and inter-individual variations in taste perception may be important risk factors for poor eating habits and obesity. Characterizing differences in taste perception and their influences on dietary intake may lead to an improved understanding of obesity risk and a potential to develop personalized nutrition recommendations. This study explored associations between 93 single nucleotide polymorphisms (SNPs) in sweet, fat, bitter, salt, sour, and umami taste receptors and psychophysical measures of taste. Forty-four families from the Guelph Family Health Study participated, including 60 children and 65 adults. Saliva was collected for genetic analysis and parents completed a three-day food record for their children. Parents underwent a test for suprathreshold sensitivity (ST) and taste preference (PR) for sweet, fat, salt, umami, and sour as well as a phenylthiocarbamide (PTC) taste status test. Children underwent PR tests and a PTC taste status test. Analysis of SNPs and psychophysical measures of taste yielded 23 significant associations in parents and 11 in children. After adjusting for multiple hypothesis testing, the rs713598 in the
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