Evidence map›Paper›PMID 30060575›Full record

ArticleCancers2018

Multimodal Radiomic Features for the Predicting Gleason Score of Prostate Cancer.

Ahmad Chaddad, Michael J Kucharczyk, Tamim Niazi

Registry-linked trialAbstract read
In one paragraph

Article in Cancers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05024162 (Can Magnetic Resonance Imaging of the Prostate Combined With a Radiomics Evaluation Determine the Invasive Capacity of a Tumour), which is not on this map. Cited by 64 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05024162 narecruitingnot on this mapstarted 2022, after this paper: background citation

Can Magnetic Resonance Imaging of the Prostate Combined With a Radiomics Evaluation Determine the Invasive Capacity of a Tumour (Can MRI-PREDICT)

TypeinterventionalSponsorNova Scotia Health AuthorityRan2022 to 2025Enrolled60ConditionsProstate CancerArmsMRT Accuracy, MRT Stability
3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ahmad ChaddadDivision of Radiation Oncology, Department of Oncology, McGill University, Montreal, QC H3S 1Y9, Canada. ahmad.chaddad@mail.mcgill.ca.ORCID 0000-0003-3402-9576
Michael J KucharczykDivision of Radiation Oncology, Department of Oncology, McGill University, Montreal, QC H3S 1Y9, Canada. michael.kucharczyk@medportal.ca.ORCID 0000-0002-2857-6840
Tamim NiaziDivision of Radiation Oncology, Department of Oncology, McGill University, Montreal, QC H3S 1Y9, Canada. tniazi@jgh.mcgill.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNovel radiomic features are enabling the extraction of biological data from routine sequences of MRI images. This study's purpose was to establish a new model, based on the joint intensity matrix (JIM), to predict the Gleason score (GS) of prostate cancer (PCa) patients.

methodsA retrospective dataset comprised of the diagnostic imaging data of 99 PCa patients was used, extracted from The Cancer Imaging Archive's (TCIA) T2-Weighted (T2-WI) and apparent diffusion coefficient (ADC) images. Radiomic features derived from JIM and the grey level co-occurrence matrix (GLCM) were extracted from the reported tumor locations. The Kruskal-Wallis test and Spearman's rank correlation identified features related to the GS. The Random Forest classifier model was implemented to identify the best performing signature of JIM and GLCM radiomic features to predict for GS.

resultsFive JIM-derived features: contrast, homogeneity, difference variance, dissimilarity, and inverse difference were independent predictors of GS (

conclusionThis retrospective study produced a novel predictive model for GS by the incorporation of JIM data from standard diagnostic MRI images.

Indexed as

biomarkersGleason scoreprostate cancerradiomics

Identifiers

PMID30060575
PMCPMC6116195

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.