ReviewMolecules (Basel, Switzerland)2018
Lignin-Derived Biomaterials for Drug Release and Tissue Engineering.
Review in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed.
- Lignin-Based Fluorescent Polymers: From Aggregation-Induced Emission Mechanism to Intelligent Bone Regeneration.Macromolecular bioscience · 2026Review
- Molecular Insights into Lignin Bioactivity: From Structural Architecture to Sustainable Food Industry Applications.International journal of molecular sciences · 2026Review
- Colloidal lignin particles for Pickering emulsion stabilization: multifunctional properties and prospects for cosmetic applications.Natural products and bioprospecting · 2026Review
- Lignin-Carbohydrate Nano-Sized Structures: An Evidence of Intracellular Lignin Biosynthesis?Plants (Basel, Switzerland) · 2026Article
- Alkali Lignin-Based Biopolymer Formulations for Electro-Assisted Drug Delivery of Natural Antioxidants in Breast Cancer Cells-A Preliminary Study.International journal of molecular sciences · 2025Article
- High-response humidity sensing with graphene oxide/lignosulfonate and laser-induced graphene for respiratory health.RSC advances · 2025Article
- Lignin from Plant-Based Agro-Industrial Biowastes: From Extraction to Sustainable Applications.Polymers · 2025Review
- Eco-friendly lignin nanoparticles as antioxidant and antimicrobial material for enhanced textile production.Scientific reports · 2024Article
- Exosomes: A New Hope for Angiogenesis-Mediated Bone Regeneration.International journal of molecular sciences · 2024Review
- Article
- Sequential catalytic lignin valorization and bioethanol production: an integrated biorefinery strategy.Biotechnology for biofuels and bioproducts · 2024Article
- Sustainable Biomass Lignin-Based Hydrogels: A Review on Properties, Formulation, and Biomedical Applications.International journal of molecular sciences · 2023Review
- Therapeutic Modulation of Cell Morphology and Phenotype of Diseased Human Cells towards a Healthier Cell State Using Lignin.Polymers · 2023Article
- Newly Synthesized Lignin Microparticles as Bioinspired Oral Drug-Delivery Vehicles: Flavonoid-Carrier Potential and In Vitro Radical-Scavenging Activity.Pharmaceutics · 2023Article
- High value valorization of lignin as environmental benign antimicrobial.Materials today. Bio · 2023Review
- Spheronized drug microcarrier system from canola straw lignin.Science and technology of advanced materials · 2023Article
- Plant Polysaccharides in Engineered Pharmaceutical Gels.Bioengineering (Basel, Switzerland) · 2022Review
- Uniformly Dispersed Poly(lactic acid)-Grafted Lignin Nanoparticles Enhance Antioxidant Activity and UV-Barrier Properties of Poly(lactic acid) Packaging Films.ACS applied polymer materials · 2022Article
- Article
- Investigation of Degradation of Composites Based on Unsaturated Polyester Resin and Vinyl Ester Resin.Materials (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Renewable resources are gaining increasing interest as a source for environmentally benign biomaterials, such as drug encapsulation/release compounds, and scaffolds for tissue engineering in regenerative medicine. Being the second largest naturally abundant polymer, the interest in lignin valorization for biomedical utilization is rapidly growing. Depending on its resource and isolation procedure, lignin shows specific antioxidant and antimicrobial activity. Today, efforts in research and industry are directed toward lignin utilization as a renewable macromolecular building block for the preparation of polymeric drug encapsulation and scaffold materials. Within the last five years, remarkable progress has been made in isolation, functionalization and modification of lignin and lignin-derived compounds. However, the literature so far mainly focuses lignin-derived fuels, lubricants and resins. The purpose of this review is to summarize the current state of the art and to highlight the most important results in the field of lignin-based materials for potential use in biomedicine (reported in 2014⁻2018). Special focus is placed on lignin-derived nanomaterials for drug encapsulation and release as well as lignin hybrid materials used as scaffolds for guided bone regeneration in stem cell-based therapies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.