Evidence map›Paper›PMID 30060484›Full record

ArticleMolecules (Basel, Switzerland)2018

Decursinol Angelate Inhibits LPS-Induced Macrophage Polarization through Modulation of the NFκB and MAPK Signaling Pathways.

Salman Ul Islam, Jung Ho Lee, Adeeb Shehzad, Eun-Mi Ahn, You Mie Lee, Young Sup Lee

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 82 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Salman Ul IslamSchool of Life Sciences, BK21 Plus KNU Creative BioResearch Group, Kyungpook National University, Daegu 41566, Korea. salman2013@knu.ac.kr.
Jung Ho LeeSchool of Life Sciences, BK21 Plus KNU Creative BioResearch Group, Kyungpook National University, Daegu 41566, Korea. quiet93@knu.ac.kr.
Adeeb ShehzadDepartment of Biomedical Engineering and Sciences, School of Mechanical and Manufacturing Engineering, National University of Sciences and Technology, Islamabad 44000, Pakistan. adeeb.shehzad@smme.nust.edu.pk.
Eun-Mi AhnDivision of Biotechnology and Convergence, Daegu 38610, Korea. ahnEM@dhu.ac.kr.
You Mie LeeCollege of Pharmacy, National Basic Research Laboratory of Vascular Homeostasis Regulation, Kyungpook National University, Daegu 41566, Korea. lym@knu.ac.kr.
Young Sup LeeSchool of Life Sciences, BK21 Plus KNU Creative BioResearch Group, Kyungpook National University, Daegu 41566, Korea. yselee@knu.ac.kr.
Kyungpook National University · KRDaegu Haany University · KRNational University of Sciences and Technology · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation is considered the root cause of various inflammatory diseases, including cancers. Decursinol angelate (DA), a pyranocoumarin compound obtained from the roots of

Indexed as

AnimalsAnti-Inflammatory AgentsBenzopyransButyratesCell PolarityCytokinesHL-60 CellsHumansLipopolysaccharidesMacrophagesMAP Kinase Signaling SystemMiceNF-kappa BPhorbol EstersProtein TransportRAW 264.7 CellsAnti-Inflammatory AgentsBenzopyransButyratesCytokinesdecursinLipopolysaccharidesNF-kappa BPhorbol Esterscytokinesdecursinol angelateinflammationMAP kinaseNFκB

Identifiers

PMID30060484
PMCPMC6222640
OpenAlexW2883649579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.