ArticleNitric oxide : biology and chemistry2018
Detection of dinitrosyl iron complexes by ozone-based chemiluminescence.
Article in Nitric oxide : biology and chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- FTO/m6A Regulate Prenatal Nicotine-Induced eNOS Uncoupling and BP Susceptibility.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Protein-bound nitrosyl iron complexes: long-lived physiological form of nitric oxide.Medical gas research · 2026Article
- Heme-NO Dilates Arteries via Mobilization of NO Moieties From an Intracellular NO Store Within Vascular Smooth Muscle Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Acute exposure to cell-free mitochondrial DNA induces pregnancy-specific aortic endothelial dysfunction and organ-selective inflammation in rats.bioRxiv : the preprint server for biology · 2026Article
- Evaluation of tetrachloroethylene (PCE) and its degradation products in human exhaled breath and indoor air in a community setting.Journal of breath research · 2024Article
- Artifacts Introduced by Sample Handling in Chemiluminescence Assays of Nitric Oxide Metabolites.Antioxidants (Basel, Switzerland) · 2023Article
- Nitric Oxide Affects Heme Oxygenase-1, Hepcidin, and Transferrin Receptor Expression in the Placenta.International journal of molecular sciences · 2023Article
- On-Site Detection of Volatile Organic Compounds (VOCs).Molecules (Basel, Switzerland) · 2023Review
- Chronic High-Altitude Hypoxia Alters Iron and Nitric Oxide Homeostasis in Fetal and Maternal Sheep Blood and Aorta.Antioxidants (Basel, Switzerland) · 2022Article
- Tri-iodide and vanadium chloride based chemiluminescent methods for quantification of nitrogen oxides.Nitric oxide : biology and chemistry · 2022Article
- Chemiluminescence Measurement of Reactive Sulfur and Nitrogen Species.Antioxidants & redox signaling · 2022Review
- Neuroprotective role of nitric oxide inhalation and nitrite in a Neonatal Rat Model of Hypoxic-Ischemic Injury.PloS one · 2022Article
- Deferoxamine produces nitric oxide under ferricyanide oxidation, blood incubation, and UV-irradiation.Free radical biology & medicine · 2020Article
- Evidence for placental-derived iron-nitrosyls in the circulation of the fetal lamb and against a role for nitrite in mediating the cardiovascular transition at birth.American journal of physiology. Regulatory, integrative and comparative physiology · 2020Article
- L-NAME releases nitric oxide and potentiates subsequent nitroglycerin-mediated vasodilation.Redox biology · 2019Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Dinitrosyl iron complexes (DNICs) are important intermediates in the metabolism of nitric oxide (NO). They have been considered to be NO storage adducts able to release NO, scavengers of excess NO during inflammatory hypotensive shock, and mediators of apoptosis in cancer cells, among many other functions. Currently, all studies of DNICs in biological matrices use electron paramagnetic resonance (EPR) for both detection and quantification. EPR is limited, however, by its ability to detect only paramagnetic mononuclear DNICs even though EPR-silent binuclear are likely to be prevalent. Furthermore, physiological concentrations of mononuclear DNICs are usually lower than the EPR detection limit (1 μM). We have thus developed a chemiluminescence-based method for the selective detection of both DNIC forms at physiological, pathophysiological, and pharmacologic conditions. We have also demonstrated the use of the new method in detecting DNIC formation in the presence of nitrite and nitrosothiols within biological fluids and tissue. This new method, which can be used alone or in tandem with EPR, has the potential to offer insight about the involvement of DNICs in many NO-dependent pathways.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.