ArticleThe British journal of radiology2018
Preoperative axillary nodal staging with ultrasound and magnetic resonance imaging: predictive values of quantitative and semantic features.
Article in The British journal of radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- The predictive value of lymph node status pre-operation by ultrasound and MRI in early and newly diagnosed breast cancer.Clinical and experimental medicine · 2026Pooled it
- Prediction of sentinel lymph node status in patients with early breast cancer using breast imaging as an alternative to surgical staging-a systematic review and meta-analysis.Systematic reviews · 2025Pooled it
- Nomogram for predicting axillary pathologic complete response in cN2-3 breast cancer after neoadjuvant chemotherapy.NPJ breast cancer · 2025Article
- At the Speed of SOUND: The Pace of Change for Axillary Management in Breast Cancer.Annals of surgical oncology · 2024Article
- High-accuracy prediction of axillary lymph node metastasis in invasive lobular carcinoma using focal cortical thickening on magnetic resonance imaging.Breast cancer (Tokyo, Japan) · 2023Article
- Multiple-parameter MRI after neoadjuvant systemic therapy combining clinicopathologic features in evaluating axillary pathologic complete response in patients with clinically node-positive breast cancer.The British journal of radiology · 2022Article
- Diffusion tensor imaging and diffusion-weighted imaging on axillary lymph node status in breast cancer patients.Diagnostic and interventional radiology (Ankara, Turkey) · 2022Article
- Imaging features of sentinel lymph node mapped by multidetector-row computed tomography lymphography in predicting axillary lymph node metastasis.BMC medical imaging · 2021Article
- Staging of the Axilla in Breast Cancer and the Evolving Role of Axillary Ultrasound.Breast cancer (Dove Medical Press) · 2021Review
- Article
- Prediction of high nodal burden with ultrasound and magnetic resonance imaging in clinically node-negative breast cancer patients.Cancer imaging : the official publication of the International Cancer Imaging Society · 2019Article
- Development and Validation of Nomograms Predictive of Axillary Nodal Status to Guide Surgical Decision-Making in Early-Stage Breast Cancer.Journal of Cancer · 2019Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objective: Although axillary imaging has recently received renewed interest for preoperative staging in tandem with the evolving minimally invasive surgical approaches, axillary imaging is limited by the lack of standardization in the interpretation. We aimed to classify imaging features in ultrasound and MRI into quantitative and semantic features and evaluate predictive value of each feature for predicting nodal metastases.
methods: A total of 316 breast cancers patients who underwent ultrasound and MRI prior to axillary surgery were included. Retrospective reviews of our breastimaging database were done for the quantitative features [cortical thickness (CT) and CT-derived parameters, long diameter (LD), short diameter (SD), and LD/SD ratio] and semantic features (eccentricity, loss of fatty hilum, and irregularity) of the axillary lymph node in images. Odd ratios (ORs) for each imaging feature were calculated with adjustment for clinicopathological characteristics significantly associated with nodal metastases.
results: All CT-derived parameters were significantly associated with nodal metastases in both ultrasound and MRI (OR, 3.3-3.5 for ultrasound and 3.3-3.9 for MRI, respectively; Ps < .05). For the ultrasound, LD/SD ratio (OR, 2.1), eccentricity (OR, 2.4), and fatty hilum loss (OR, 27.2) were significantly associated with nodal metastases (Ps < .05). For the MRI, SD (OR, 2.1) and eccentricity (OR, 3.0) were significantly associated with nodal metastases (Ps < .05).
conclusion: Among the quantitative features, all CT-derived parameters can be used for predicting nodal metastases. Significant predictors of semantic features were heterogeneous between ultrasound and MRI. ADVANCES IN KNOWLEDGE:: (1) Imaging features of ultrasound and MRI for preoperative axillary nodal staging can be classified into quantitative and semantic features. (2) Predictive values of each imaging features are heterogeneous for predicting nodal metastases.
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