ReviewArthritis & rheumatology (Hoboken, N.J.)2018
Interstitial Pneumonia With Autoimmune Features: An Emerging Challenge at the Intersection of Rheumatology and Pulmonology.
Review in Arthritis & rheumatology (Hoboken, N.J.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Clinical and serological predictors of autoimmune etiology in patients with interstitial lung disease: a 10-year retrospective study.Clinical rheumatology · 2026Article
- Machine Learning of Plasma Proteomics Classifies Diagnosis of Interstitial Lung Disease.American journal of respiratory and critical care medicine · 2024Article
- Characterizing the lavage and serum cytokine profiles of interstitial pneumonia with autoimmune features and their implications for progressive fibrosis.Rheumatology (Oxford, England) · 2024Article
- Monitoring small airway dysfunction in connective tissue disease-related interstitial lung disease: a retrospective and prospective study.BMC pulmonary medicine · 2023Article
- Recurrent Exacerbations and Evolution into Polymyositis in a Patient with Interstitial Pneumonia with Autoimmune Features: A Case Report and Literature Review.Medicina (Kaunas, Lithuania) · 2023Review
- Interstitial Pneumonia with Autoimmune Features: What the Rheumatologist Needs to Know.Current rheumatology reports · 2022Review
- Antisynthetase Syndrome Post Shingrix and Pneumovax Vaccinations, Possible Correlation.Cureus · 2022Article
- Interstitial pneumonia with autoimmune features: challenges and controversies.European respiratory review : an official journal of the European Respiratory Society · 2021Review
- Rituximab for interstitial pneumonia with autoimmune features at two medical centres.Rheumatology advances in practice · 2021Article
- Real world utilization of the myositis autoantibody panel.Clinical rheumatology · 2021Article
- Risk of progression of idiopathic pulmonary fibrosis to connective tissue disease: a long-term observational study in 527 patients.Clinical rheumatology · 2021Observational
- Successful treatment of severe interstitial pneumonia by removal of circulating autoantibodies: a case series.BMC pulmonary medicine · 2021Article
- Efficacy and safety of mycophenolate mofetil in the treatment of rheumatic disease-related interstitial lung disease: a narrative review.Drugs in context · 2021Review
- Connective tissue disease-related interstitial lung disease (CTD-ILD) and interstitial lung abnormality (ILA): Evolving concept of CT findings, pathology and management.European journal of radiology open · 2021Review
- Article
- Interstitial Pneumonia with Autoimmune Features: Why Rheumatologist-Pulmonologist Collaboration Is Essential.Biomedicines · 2020Review
- Myositis-specific antibodies identify a distinct interstitial pneumonia with autoimmune features phenotype.The European respiratory journal · 2020Article
- Interstitial pneumonia with autoimmune features in a patient with melanoma differentiation-associated gene 5 (MDA5) antibody.BMJ case reports · 2020Article
- Interstitial Pneumonia with Autoimmune Features (IPAF): A Single-Centre, Prospective Study.Mediterranean journal of rheumatology · 2020Article
- Lung Involvement in Primary Sjögren's Syndrome-An Under-Diagnosed Entity.Frontiers in medicine · 2020Article
Corrections and comments
Authors and funding
9 authors.
Funding
Abstract
Interstitial lung disease (ILD) remains a cause of significant morbidity and mortality in patients with connective tissue disease (CTD)-associated ILD. While some patients meet clear classification criteria for a systemic rheumatic disease, a subset of patients do not meet classification criteria but still benefit from immunosuppressive therapy. In 2015, the American Thoracic Society and European Respiratory Society described classification criteria for interstitial pneumonia with autoimmune features (IPAF) to identify patients with lung-predominant CTD who lack sufficient features of a systemic rheumatic disease to meet classification criteria. Although these criteria are imperfect, they are an important attempt to classify the patient with undifferentiated disease for future study. Rheumatologists play a key role in the evaluation of potential IPAF in patients, especially as many patients with a myositis-spectrum disease (e.g., non-Jo-1 antisynthetase syndrome, anti-melanoma differentiation-associated protein 5 antibody inflammatory myositis, or anti-PM/Scl antibody-associated inflammatory myositis) would be classified under IPAF using the currently available criteria for inflammatory myositis, and would therefore benefit from rheumatologic comanagement. The aim of this review was to describe the historical context that led to the development of these criteria and to discuss the limitations of the current criteria, diagnostic challenges, treatment options, and strategies for disease monitoring.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.