ArticleTransboundary and emerging diseases2018
An outbreak of tuberculosis due to Mycobacterium bovis infection in a pack of English Foxhounds (2016-2017).
Article in Transboundary and emerging diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 29 citations in OpenAlex.
- Mycobacterium tuberculosis complex species-induced infections in dogs: a narrative review of five cases reported in Brazil (1990-2024).Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Review
- Case Report: Epidemiologically inferred reverse zoonosis and intra-household zoonotic re-exposure ofFrontiers in veterinary science · 2026Article
- Comparative Performance of Ante-Mortem Diagnostic Assays for the Identification ofPathogens (Basel, Switzerland) · 2025Article
- Cytokine and Chemokine Responses of Peripheral Blood Mononuclear Cells from Dogs Infected withPathogens (Basel, Switzerland) · 2024Article
- Mycobacterium tuberculosis infection in a free-ranging urban dog from Argentina.Veterinary research communications · 2022Article
- Diagnostic and public health investigation ofJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2022Article
- Serial Interferon-Gamma Release Assay (IGRA) Testing to Monitor Treatment Responses in Cases of Feline Mycobacteriosis.Pathogens (Basel, Switzerland) · 2021Article
- Article
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- Emerging source of infection -Access microbiology · 2020Article
- The Welfare of Pig-Hunting Dogs in Australia.Animals : an open access journal from MDPI · 2019Review
- Tuberculosis in UK cats associated with a commercial raw food diet.Journal of feline medicine and surgery · 2019Article
- Tuberculosis due toJournal of feline medicine and surgery · 2019Article
- An outbreak of tuberculosis due to Mycobacterium bovis infection in a pack of English Foxhounds (2016-2017).Transboundary and emerging diseases · 2018Article
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11 authors at 2 institutions in 1 country.
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Abstract
Mycobacterium bovis can cause tuberculosis (TB) in social mammals including lions, cattle and man, but canine infections are considered rare. In 2016/17 we investigated a M. bovis TB outbreak in a pack of approximately 180 Foxhounds within the bovine TB Edge Area of England. We employed a combination of immunological tests including an interferon gamma release assay (IGRA) and a serological assay (DPP VetTB, Chembio). Test-positive hounds were euthanased and subjected to post-mortem examination (PME). Overall 164 hounds were tested; 97 (59%) responded positively to at least one test. Eighty-five (52%) dogs responded to M. bovis antigens by IGRA while only 21 (12.9%) had detectable serological responses. At PME three hounds (3.1%) had visible lesions (VL) due to M. bovis infection, later confirmed by culture. Samples from 24 non-VL hounds were cultured and M. bovis infection was confirmed in a further three hounds (11%). This study is the first investigation and report of an outbreak of M. bovis TB in a canine species. We establish that, in principle, diagnostic tests used for identifying infected individuals of other species can effectively be used in the dog. Further work is urgently needed to establish the sensitivity and specificity of the testing approach used in this study for future clinical application.
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