ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2018
Case-specific non-linear finite element models to predict failure behavior in two functional spinal units.
Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 29 citations in OpenAlex.
- Fracture Patterns of an Osteolytic Hole Involved Lumbar Vertebra, Assessed for a Case Study by Computational Models.International journal for numerical methods in biomedical engineering · 2026Article
- A Review of Finite Element Analysis in Spine Surgery Decision-Making.Journal of clinical medicine · 2026Review
- Poroelastic Characterization of Human Vertebral Metastases to Inform a Transdisciplinary Assessment of Spinal Tumors.Journal of clinical medicine · 2025Article
- Geometric determinants of the mechanical behavior of image-based finite element models of the intervertebral disc.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024Article
- Finite element investigation of the influence of a new transpedicular vertebral implant positioning on biomechanical responses of the spine segment.Medical engineering & physics · 2024Article
- Effect of cement volume on biomechanical response of a spine segment treated with a PEEK polymer implant: a finite element comparative study with vertebroplasty.Frontiers in bioengineering and biotechnology · 2024Article
- Influence of image reconstruction kernel on computed tomography-based finite element analysis in the clinical opportunistic screening of osteoporosis-A preliminary result.Frontiers in endocrinology · 2023Article
- Experimental validation of a subject-specific finite element model of lumbar spine segment using digital image correlation.PloS one · 2022Article
- Review
- MDCT-Based Finite Element Analysis for the Prediction of Functional Spine Unit Strength-An In Vitro Study.Materials (Basel, Switzerland) · 2021Article
- Multi-detector computed tomography (MDCT) imaging: association of bone texture parameters with finite element analysis (FEA)-based failure load of single vertebrae and functional spinal units.Quantitative imaging in medicine and surgery · 2021Article
- MDCT-Based Finite Element Analyses: Are Measurements at the Lumbar Spine Associated with the Biomechanical Strength of Functional Spinal Units of Incidental Osteoporotic Fractures along the Thoracolumbar Spine?Diagnostics (Basel, Switzerland) · 2021Article
- Fracture risk assessment and clinical decision making for patients with metastatic bone disease.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020Review
- Mechanical testing setups affect spine segment fracture outcomes.Journal of the mechanical behavior of biomedical materials · 2019Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Current finite element (FE) models predicting failure behavior comprise single vertebrae, thereby neglecting the role of the posterior elements and intervertebral discs. Therefore, this study aimed to develop a more clinically relevant, case-specific non-linear FE model of two functional spinal units able to predict failure behavior in terms of (i) the vertebra predicted to fail; (ii) deformation of the specimens; (iii) stiffness; and (iv) load to failure. For this purpose, we also studied the effect of different bone density-mechanical properties relationships (material models) on the prediction of failure behavior. Twelve two functional spinal units (T6-T8, T9-T11, T12-L2, and L3-L5) with and without artificial metastases were destructively tested in axial compression. These experiments were simulated using CT-based case-specific non-linear FE models. Bone mechanical properties were assigned using four commonly used material models. In 10 of the 11 specimens our FE model was able to correctly indicate which vertebrae failed during the experiments. However, predictions of the three-dimensional deformations of the specimens were less promising. Whereas stiffness of the whole construct could be strongly predicted (R
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