ArticleJournal of clinical hypertension (Greenwich, Conn.)2018
Nocturnal blood pressure patterns and cardiovascular outcomes in patients with masked hypertension.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
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- Review
- Youth Blood Pressure and Target Organ Injury Markers: The SHIP AHOY Study.Hypertension (Dallas, Tex. : 1979) · 2025Article
- The relationship between ambulatory arterial stiffness index and incident atrial fibrillation.Clinical cardiology · 2024Observational
- Hypertension in Wilms tumor.Pediatric nephrology (Berlin, Germany) · 2024Review
- Prevalence of Isolated Nocturnal Hypertension and Development of Arterial Stiffness, Left Ventricular Hypertrophy, and Silent Cerebrovascular Lesions: The KoGES (Korean Genome and Epidemiology Study).Journal of the American Heart Association · 2022Article
- Heart rate turbulence measurements in patients with dipper and non-dipper hypertension: the effects of autonomic functionsTurkish journal of medical sciences · 2021Article
- ARB-Based Combination Therapy for the Clinical Management of Hypertension and Hypertension-Related Comorbidities: A Spotlight on Their Use in COVID-19 Patients.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021Review
- The relationship between ambulatory arterial stiffness, inflammation, blood pressure dipping and cardiovascular outcomes.BMC cardiovascular disorders · 2021Observational
- Association Between Bedtime at Night and Systolic Blood Pressure in Adults in NHANES.Frontiers in medicine · 2021Article
- Blood Pressure Target Achievement Under Monotheraphy: A Real-Life Appraisal.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2020Observational
- Isolated Nocturnal Hypertension: What Do We Know and What Can We Do?Integrated blood pressure control · 2020Review
- Nocturnal dipping status and the association of morning blood pressure surge with subclinical target organ damage in untreated hypertensives.Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
- Relationship Between Outpatient Clinic and Ambulatory Blood Pressure Measurements and Mortality.Current cardiology reports · 2019Review
- Nocturnal blood pressure patterns and cardiovascular outcomes in patients with masked hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2018Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Masked hypertension (MHT) is characterized by normal clinic and above normal 24-hour ambulatory blood pressure (BP) levels. We evaluated clinical characteristics and CV outcomes of different nocturnal patterns of MHT. We analyzed data derived from a large cohort of adult individuals, who consecutively underwent home, clinic, and ambulatory BP monitoring at our Hypertension Unit between January 2007 and December 2016. MHT was defined as clinic BP <140/90 mm Hg and 24-hour BP ≥ 130/80 mm Hg, and stratified into three groups according to dipping status: (a) dippers, (b) nondippers, and (c) reverse dippers. From an overall sample of 6695 individuals, we selected 2628 (46.2%) adult untreated individuals, among whom 153 (5.0%) had MHT. In this group, 67 (43.8%) were nondippers, 65 (42.5%) dippers, and 21 (13.7%) reverse dippers. No significant differences were found among groups regarding demographics, clinical characteristics, and prevalence of risk factors, excluding older age in reverse dippers compared to other groups (P < 0.001). Systolic BP levels were significantly higher in reverse dippers than in other groups at both 24-hour (135.6 ± 8.5 vs 130.4 ± 6.0 vs 128.2 ± 6.8 mm Hg, respectively; P < 0.001) and nighttime periods (138.2 ± 9.1 vs 125.0 ± 6.3 vs 114.5 ± 7.7 mm Hg; P < 0.001). Reverse dipping was associated with a significantly higher risk of stroke, even after correction for age, gender, BMI, dyslipidemia, and diabetes (OR 18.660; 95% IC [1.056-33.813]; P = 0.046). MHT with reverse dipping status was associated with higher burden of BP and relatively high risk of stroke compared to both dipping and nondipping profiles, although a limited number of CV outcomes have been recorded during the follow-up.
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