ReviewCurrent neurology and neuroscience reports2018
Photophobia: When Light Hurts, a Review.
Review in Current neurology and neuroscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 48 citations in OpenAlex.
- The Dark Side of Light: Spectral Variation in Post-Traumatic Photosensitivity and Its Functional Sequelae.Brain sciences · 2026Article
- A timeline of structural and functional consequences to ipRGCs in a mouse model of Alzheimer's disease.Neurobiology of aging · 2026Article
- Supporting Students with Migraine: Examining Current Practices and Identifying Strategies for Educational Success.Current pain and headache reports · 2025Review
- Formoterol dynamically alters endocannabinoid tone in the periaqueductal gray inducing headache.The journal of headache and pain · 2024Article
- The Role of Season, Sunlight, and Light Sensitivity in Self-Reported Depressive Symptoms by Adults With Visual Impairment.Translational vision science & technology · 2024Article
- Article
- Hypersensitivity of Intrinsically Photosensitive Retinal Ganglion Cells in Migraine Induces Cortical Spreading Depression.International journal of molecular sciences · 2024Article
- Visual Snow Syndrome in Patient with Migraine: Case Report and Literature Review.Journal of clinical medicine · 2024Review
- Psychometric Properties of the Persian Translation of the 12-Item Utah Photophobia Symptom Impact Scale Questionnaire.Neuro-ophthalmology (Aeolus Press) · 2024Article
- Multiprofessional Neurorehabilitation After COVID-19 Infection Should Include Assessment of Visual Function.Archives of rehabilitation research and clinical translation · 2022Article
- Photophobia and migraine outcome during treatment with galcanezumab.Frontiers in neurology · 2022Article
- Spatial sensitivity of human circadian response: Melatonin suppression from on-axis and off-axis light exposures.Neurobiology of sleep and circadian rhythms · 2021Article
- Development and Feasibility of the Headache-Related Light and Sound Sensitivity Inventories in Youth.Children (Basel, Switzerland) · 2021Article
- Mechanisms and Pathways of Pain Photobiomodulation: A Narrative Review.The journal of pain · 2021Review
- Supraspinal Mechanisms Underlying Ocular Pain.Frontiers in medicine · 2021Review
- Managing Photophobia with the Utilisation of Smart Light Bulbs.Neuro-ophthalmology (Aeolus Press) · 2021Article
- Connections between intrinsically photosensitive retinal ganglion cells and TBI symptoms.Neurology · 2020Review
- Wavelength of light and photophobia in inherited retinal dystrophy.Scientific reports · 2020Article
- Favorable Effects of Tacrolimus Monotherapy on Myasthenia Gravis Patients.Frontiers in neurology · 2020Article
- Blue light activates pulvinar nuclei in longstanding idiopathic photophobia: A case report.NeuroImage. Clinical · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewTo provide an updated overview of Photophobia with a particular focus on photophobia related to migraine. RECENT
findingsMelanopsin-containing photoreceptors called intrinsically photosensitive retinal ganglion cells (ipRGCs) have been identified in the retina and explain the rational for photophobia in individuals who are blind. Photophobia, a sensory disturbance provoked by light, is a common neurological and ophthalmological symptom. Migraine, a common neurological condition, is pathognomonic of photophobia; however, other primary headache conditions, traumatic brain injury, and impairment of the optic pathway can cause photophobia. In addition, anterior and posterior segment ocular pathology, medications, and psychiatric conditions can result in photophobia. At least 2 (possibly three) distinct neural pathways are involved in photophobia. Some of the basic science regarding these pathways is discussed in this review including the role of calcitonin gene-related peptide (CGRP) and pituitary adenylate cyclase-activating polypeptide. Management of photophobia includes treatment of the underlying etiology and conservative strategies such as wearing sunglasses.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.