ArticleEnvironmental science and pollution research international2018
Associations of potentially toxic elements (PTEs) in drinking water and human biomarkers: a case study from five districts of Pakistan.
Article in Environmental science and pollution research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Trace Mineral Imbalances in Global Health: Challenges, Biomarkers, and the Role of Serum Analysis.Nutrients · 2025Review
- Assessment of the Pollution Load of Effluents Discharged from Higher Institutions in Ethiopia: The Case of Bahir Dar University Zenzelma Campus.International journal of analytical chemistry · 2022Article
- Potentially toxic elements' occurrence and risk assessment through water and soil of Chitral urban environment, Pakistan: a case study.Environmental geochemistry and health · 2020Article
- Evaluation of the Swat River, Northern Pakistan, water quality using multivariate statistical techniques and water quality index (WQI) model.Environmental science and pollution research international · 2020Article
- Human health risks by potentially toxic metals in drinking water along the Hattar Industrial Estate, Pakistan.Environmental science and pollution research international · 2020Article
- Copper and other heavy metals in grapes: a pilot study tracing influential factors and evaluating potential risks in China.Scientific reports · 2018Article
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Authors and funding
3 authors.
Funding
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Abstract
Potentially toxic elements (PTEs) are hazardous contaminants with great global environmental/ecological concerns due to their toxic, persistence, and bio-accumulative nature. This study investigates the concentrations of PTEs (Cd, Co, Cu, Fe, Ni, Mn, Pb, and Zn) in drinking water sources and consumers' biomarkers such as hair, nails, urine, and blood. For this purpose, drinking water (n = 190) and consumer biomarker (n = 60) samples were collected from five districts of the Southern Khyber Pakhtunkhwa, Pakistan. Samples were extracted and analyzed for selected PTEs concentrations using an inductively coupled plasma mass spectrometer (ICP-MS, PerkinElmer Optima 7000 DV, USA). The concentrations of PTEs were observed within the drinking water guidelines set by the World Health Organization (WHO), except for Fe, Mn, and Pb. The determined concentrations of PTEs were used to evaluate the health risk through exposure, particularly hazard quotient (HQ) and hazard index (HI). The PTEs contamination of drinking water has led to the highest mean ADI values (39.0 and 91.8 μg/kg/day) and HQ values (0.306 and 0.130) for Zn in adults and children, respectively. The mean values of HQ and HI for selected PTEs were observed within the safe health limits (< 1). Among studied biomarkers, hair showed the highest concentrations for Mn, Zn, Cd, and Pb, plasma for Co and Cu, nails for Ni, and red blood cells (RBCs) for Fe only. This study concluded that chronic exposure of PTEs through drinking water consumption has led to their bioaccumulation in human biomarkers.
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