Evidence map›Paper›PMID 30057909›Full record

Trial reportBioMed research international2018

Oxytocin Administration in High-Intensity Focused Ultrasound Treatment of Myomata.

Tomasz Lozinski, Justyna Filipowska, Piotr Krol, Anna Kubaty, Piotr Wegrzyn

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Tomasz LozinskiSpecialist Hospital Pro-Familia, Rzeszow, Poland.
Justyna FilipowskaSpecialist Hospital Pro-Familia, Rzeszow, Poland.
Piotr KrolSpecialist Hospital Pro-Familia, Rzeszow, Poland.
Anna KubatyDepartment of Obstetrics, Gynecology and Oncology, The Gabriel Narutowicz Hospital, Krakow, Poland.
Piotr WegrzynDepartment of Obstetrics and Perinatology, Faculty of Health Sciences, Medical University of Warsaw, Zwirki i Wigury Str. 63a, 02-091 Warsaw, Poland.ORCID 0000-0002-9876-8493
Medical University of Warsaw · PLUniversity of Rzeszów · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of the study was to evaluate the clinical efficacy of magnetic resonance-guided High-Intensity Focused Ultrasound (HIFU) in patients with symptomatic uterine fibroids (myomata) after application of oxytocin.

methods156 women with symptomatic uterine fibroids were treated using MR-guided HIFU procedure. 51 patients had additional IV administration of 40 IU of oxytocin in 5% Glucose or 0,9% NaCl solution during therapy. Before and after the procedure we performed MR and measured initial perfused volume, final perfused volume, nonperfused volume (NPV), and treated volume ratio (TVR). The follow-up was up to 15 months to assess efficacy of treatment and relief of symptoms.

resultsNonperfused volume was statistically significantly larger in oxytocin group than in control group (p=0.0019). The remaining parameters did not show significant difference between both groups.

conclusionOxytocin administration seems to improve efficiency of HIFU therapy although further research is required to assess its value. This study' clinical registration number is DRKS00014794.

Indexed as

High-Intensity Focused Ultrasound AblationFemaleHumansLeiomyomaMagnetic Resonance ImagingMyomaOxytocicsOxytocinTreatment OutcomeUterine NeoplasmsOxytocicsOxytocin

Identifiers

PMID30057909
PMCPMC6051281
OpenAlexW2809839920

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.