ReviewF1000Research2018
The role of the gut microbiome during host ageing.
Review in F1000Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Age-Dependent Gut Microbiota Dynamics and Their Association with Male Life-History Traits in Drosophila melanogaster.Microbial ecology · 2025Article
- Insight into the Skin Mycobiota ofAnimals : an open access journal from MDPI · 2025Article
- Microbiota-Accessible Borates as Novel and Emerging Prebiotics for Healthy Longevity: Current Research Trends and Perspectives.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Beyond microbial abundance: metadata integration enhances disease prediction in human microbiome studies.Frontiers in microbiology · 2025Article
- Association between Accelerated Biological Aging, Diet, and Gut Microbiome.Microorganisms · 2024Review
- c-Jun N-terminal kinase signaling in aging.Frontiers in aging neuroscience · 2024Review
- Microbiome variations among age classes and diets of captive Asian elephants (Elephas maximus) in Thailand using full-length 16S rRNA nanopore sequencing.Scientific reports · 2023Article
- Impact of Gut Microbiota in Brain Ageing: Polyphenols as Beneficial Modulators.Antioxidants (Basel, Switzerland) · 2023Review
- Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain.Microbiome · 2022Article
- Effects of Growth Stage and Rearing Pattern on Pig Gut Microbiota.Current microbiology · 2022Article
- The Role of Microbiota inFrontiers in aging · 2022Review
- Metformin Attenuates Inflammatory Responses and Enhances Antibody Production in an Acute Pneumonia Model ofFrontiers in aging · 2022Article
- Article
- Temporal Transcriptomics of Gut Escherichia coli in Caenorhabditis elegans Models of Aging.Microbiology spectrum · 2021Article
- Age-related changes in intestinal immunity and the microbiome.Journal of leukocyte biology · 2021Review
- A Cross-Sectional Study of the Gut Microbiota Composition in Moscow Long-Livers.Microorganisms · 2020Article
- Benefits of Metformin in Attenuating the Hallmarks of Aging.Cell metabolism · 2020Review
- Temporal, Environmental, and Biological Drivers of the Mucosal Microbiome in a Wild Marine Fish, Scomber japonicus.mSphere · 2020Article
- Building upon current knowledge and techniques of indoor microbiology to construct the next era of theory into microorganisms, health, and the built environment.Journal of exposure science & environmental epidemiology · 2020Review
- The Transformative Possibilities of the Microbiota and Mycobiota for Health, Disease, Aging, and Technological Innovation.Biomedicines · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gut microbial communities participate in key aspects of host biology, including development, nutrient absorption, immunity and disease. During host ageing, intestinal microbes undergo dramatic changes in composition and function and can shift from commensal to pathogenic. However, whether they play a causal role in host ageing and life span has remained an open question for a long time. Recent work in model organisms has revealed for the first time that gut microbes can modulate ageing, opening new questions and opportunities to uncover novel ageing-modulating mechanisms and to design anti-ageing interventions by targeting the gut microbiota.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.