Evidence map›Paper›PMID 30057694›Full record

ArticleToxicological research2018

Metabolic Profiling of Eccentric Exercise-Induced Muscle Damage in Human Urine.

Hyun-Jun Jang, Jung Dae Lee, Hyun-Sik Jeon, Ah-Ram Kim, Suhkmann Kim, Ho-Seong Lee, Kyu-Bong Kim

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Toxicological research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07728422 (Effects of Ozone Therapy Modalities on Biochemical Markers of Muscle Damage Following Eccentric Exercise), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07728422 nacompletednot on this mapstarted 2024, after this paper: background citation

Effects of Ozone Therapy Modalities on Biochemical Markers of Muscle Damage Following Eccentric Exercise

TypeinterventionalSponsorInonu UniversityRan2024 to 2025Enrolled32ConditionsOzone Therapy, Muscle Damage, Oxidative Stress, RecoveryArmsAutohemotherapy, Ozone Sauna Therapy, Ozonated Lavender Oil Massage
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Metabolomics in Exercise and Sports: A Systematic Review.Sports medicine (Auckland, N.Z.) · 2022
    Pooled it
  3. Article
  4. Review
  5. Review
  6. NMR-based metabolomics profile during a soccer season of a sub-elite soccer team.Metabolomics : Official journal of the Metabolomic Society · 2026
    Article
  7. Article
  8. Energy production pathways of female soccer players during championships: a metabolomics approach.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
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  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Hyun-Jun JangCollege of Pharmacy, Dankook University, Cheonan, Korea.
Jung Dae LeeDivision of Toxicology, College of Pharmacy, Sungkyunkwan University, Suwon, Korea.
Hyun-Sik JeonDepartment of Kinesiologic Medical Science, Graduate School, Dankook University, Cheonan, Korea.
Ah-Ram KimDepartment of Kinesiologic Medical Science, Graduate School, Dankook University, Cheonan, Korea.
Suhkmann KimDepartment of Chemistry and Chemistry Institute of Functional Materials, Pusan National University, Busan, Korea.
Ho-Seong LeeDepartment of Kinesiologic Medical Science, Graduate School, Dankook University, Cheonan, Korea.
Kyu-Bong KimCollege of Pharmacy, Dankook University, Cheonan, Korea.
Dankook University · KRNamseoul University · KRPusan National University · KRSungkyunkwan University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skeletal muscle can be ultrastructurally damaged by eccentric exercise, and the damage causes metabolic disruption in muscle. This study aimed to determine changes in the metabolomic patterns in urine and metabolomic markers in muscle damage after eccentric exercise. Five men and 6 women aged 19~23 years performed 30 min of the bench step exercise at 70 steps per min at a determined step height of 110% of the lower leg length, and stepping frequency at 15 cycles per min.

Indexed as

Eccentric exerciseMetabolomic analysisSex-dependent patternsSkeletal muscle

Identifiers

PMID30057694
PMCPMC6057290
OpenAlexW2620628336

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.