Evidence map›Paper›PMID 30057677›Full record

ArticleOxidative medicine and cellular longevity2018

Blackberry and Blueberry Anthocyanin Supplementation Counteract High-Fat-Diet-Induced Obesity by Alleviating Oxidative Stress and Inflammation and Accelerating Energy Expenditure.

Tao Wu, Yufang Gao, Xueqi Guo, Min Zhang, Lingxiao Gong

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
5.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 114 citations in OpenAlex.

  1. Potential of anthocyanin as an anti-inflammatory agent: a human clinical trial on type 2 diabetic, diabetic at-risk and healthy adults.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2021
    Trial
  2. Trial
  3. Article
  4. Palmitoylethanolamide in Human and Animal Obesity.Molecules (Basel, Switzerland) · 2026
    Review
  5. Review
  6. Review
  7. Wild blueberries and cardiometabolic health: a current review of the evidence.Critical reviews in food science and nutrition · 2026
    Review
  8. Article
  9. Article
  10. Moro Orange (International journal of molecular sciences · 2025
    Article
  11. Review
  12. Drying: A Practical Technology for Blueberries (Antioxidants (Basel, Switzerland) · 2024
    Article
  13. Antioxidant Activity of Anthocyanins and Anthocyanidins: A Critical Review.International journal of molecular sciences · 2024
    Review
  14. Blueberry (Foods (Basel, Switzerland) · 2024
    Review
  15. Review
  16. Review
  17. Current pharmaceutical biotechnology · 2024
    Article
  18. Review
  19. Article
  20. Optimization of Phloretin-loaded Nanospanlastics for Targeting ofCurrent pharmaceutical biotechnology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Tao WuKey Laboratory of Food Nutrition and Safety (Tianjin University of Science and Technology), Ministry of Education, Tianjin 300457, China.ORCID 0000-0002-0629-8421
Yufang GaoKey Laboratory of Food Nutrition and Safety (Tianjin University of Science and Technology), Ministry of Education, Tianjin 300457, China.
Xueqi GuoKey Laboratory of Food Nutrition and Safety (Tianjin University of Science and Technology), Ministry of Education, Tianjin 300457, China.
Min ZhangKey Laboratory of Food Nutrition and Safety (Tianjin University of Science and Technology), Ministry of Education, Tianjin 300457, China.ORCID 0000-0003-3114-8609
Lingxiao GongBeijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology & Business University, Beijing, China.ORCID 0000-0001-9075-513X
Tianjin University of Science and Technology · CNBeijing Technology and Business University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many studies indicate that an anthocyanin-rich diet has beneficial effects preventing metabolic disease. In the present study, the molecular mechanism underlying the antiobesity effect of consuming blackberry anthocyanins (BLA) and blueberry anthocyanins (BBA) was investigated in high-fat-diet- (HFD-) fed C57BL/6 mice. Sixty mice were administered a low-fat diet (LFD), a HFD, or a HFD plus orlistat, and BLA or BBA in their daily food for 12 weeks. As a result, the consumption of BLA and BBA inhibited body weight gain by 40.5% and 55.4%, respectively, in HFD-fed mice. The BLA and BBA treatments markedly reduced serum and hepatic lipid levels and significantly increased hepatic superoxide dismutase and glutathione peroxidase activities. In addition, the treatments effectively increased fecal acetate and butyrate levels and significantly attenuated expression of tumor necrosis factor TNF-

Indexed as

AnimalsAnthocyaninsBlueberry PlantsEnergy MetabolismGlutathione PeroxidaseInflammationInterleukin-6Lipid MetabolismMaleMiceMice, Inbred C57BLObesityOxidative StressRubusSuperoxide DismutaseTumor Necrosis Factor-alphaAnthocyaninsGlutathione PeroxidaseInterleukin-6Superoxide DismutaseTumor Necrosis Factor-alpha

Identifiers

PMID30057677
PMCPMC6051031
OpenAlexW2809767017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.