ArticleJournal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience2018
Reviewing the Diverse Effects of Protein Phosphorylation in Neural Signaling Transduction.
Article in Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- PamgeneAnalyzeR: open and reproducible pipeline for kinase profiling.Bioinformatics (Oxford, England) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Signaling transduction pathways are now known to be foundational mechanisms for a wide variety of biological function. Nobel laureate Paul Greengard dedicated his early career to the exploration of how these molecular cascades are triggered by neurotransmitters, hence applying a general phenomenon to the nervous system. A review by Hemmings, Nairn, McGuinness, Huganir, and Greengard published in the FASEB journal in 1989 identifies three different effects of protein phosphorylation, namely vesicle release, modulation of receptor sensitivity, and initiation of positive or negative feedback systems. The work's focus on three specific examples, rather than the exhaustive approach taken by many other reviews, provides students with an accessible framework within which to learn fundamental concepts in molecular neuroscience. The review could be incorporated as assigned reading for introductory neuroscience or even upper level molecular neurobiology, as it holds very versatile teaching potential.
Indexed as
Identifiers
30057512PMC6057775What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.