ArticleCurrent biology : CB2018
Discovery of a New Song Mode in Drosophila Reveals Hidden Structure in the Sensory and Neural Drivers of Behavior.
Article in Current biology : CB, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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48 citing papers in PubMed, 91 citations in OpenAlex.
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- Sex-specific behavioral feedback modulates sensorimotor processing and drives flexible social behavior.Nature communications · 2026Article
- Recent social experience alters song behavior in Drosophila.Current biology : CB · 2026Article
- Sequencing of distinct wing behaviors during Drosophila courtship.Current biology : CB · 2026Article
- Neural evolution of complex motor behaviors: insights from Drosophila courtship song.Current opinion in neurobiology · 2025Review
- A neural circuit for context-dependent multimodal signaling in Drosophila.Nature communications · 2025Article
- Neural control of coordinated wing and leg movements during a terrestrial threat display.bioRxiv : the preprint server for biology · 2025Article
- Sequencing of distinct wing behaviors duringbioRxiv : the preprint server for biology · 2025Article
- Recombinant inbred line panels inform the genetic architecture and interactions of adaptive traits in Drosophila melanogaster.G3 (Bethesda, Md.) · 2025Article
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- Courtship song differs between African and European populations of Drosophila melanogaster and involves a strong effect locus.G3 (Bethesda, Md.) · 2025Article
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- Single-cell type analysis of wing premotor circuits in the ventral nerve cord ofbioRxiv : the preprint server for biology · 2025Article
- Neurons Underlying Aggression-Like Actions That Are Shared by Both Males and Females inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Activity of nested neural circuits drives different courtship songs in Drosophila.Nature neuroscience · 2024Article
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- Male-male interactions shape mate selection inbioRxiv : the preprint server for biology · 2023Article
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8 authors at 1 institution in 1 country.
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Abstract
Deciphering how brains generate behavior depends critically on an accurate description of behavior. If distinct behaviors are lumped together, separate modes of brain activity can be wrongly attributed to the same behavior. Alternatively, if a single behavior is split into two, the same neural activity can appear to produce different behaviors. Here, we address this issue in the context of acoustic communication in Drosophila. During courtship, males vibrate their wings to generate time-varying songs, and females evaluate songs to inform mating decisions. For 50 years, Drosophila melanogaster song was thought to consist of only two modes, sine and pulse, but using unsupervised classification methods on large datasets of song recordings, we now establish the existence of at least three song modes: two distinct pulse types, along with a single sine mode. We show how this seemingly subtle distinction affects our interpretation of the mechanisms underlying song production and perception. Specifically, we show that visual feedback influences the probability of producing each song mode and that male song mode choice affects female responses and contributes to modulating his song amplitude with distance. At the neural level, we demonstrate how the activity of four separate neuron types within the fly's song pathway differentially affects the probability of producing each song mode. Our results highlight the importance of carefully segmenting behavior to map the underlying sensory, neural, and genetic mechanisms.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.