ArticleNeuron2018
Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning.
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Article in Neuron, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.
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98citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
What it found
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Who cites it
98 citing papers in PubMed, 143 citations in OpenAlex.
- Interaction between N6-methyladenosine (mGenes & diseases · 2026Review
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- The m⁶A reader YTHDF2 regulates mRNA transport and axon outgrowth in developing neurons.Nature communications · 2026Article
- Neuronal YTHDF2 suppresses innate immune activation in Aβ pathology by promoting mScience advances · 2026Article
- m6A deficiency induces dopaminergic neurodegeneration and progressive parkinsonism through a pathogenic loop with mitochondria.The Journal of clinical investigation · 2026Article
- mRNA mProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Loss of METTL14 in dopaminergic neurons disrupts ER homeostasis via m6A-dependent regulation of Atp2a3 mRNA: Implications for Parkinson's Disease.NPJ Parkinson's disease · 2026Article
- Inhibition of N6-Methyladenosine Accumulation by Targeting METTL3 Mitigates Tau Pathology and Cognitive Decline in Alzheimer's Disease.Research square · 2025Article
- RNA methylation modifications in neurodegenerative diseases: Focus on their enzyme system.Journal of advanced research · 2025Review
- Erasing "bad memories": reversing aberrant synaptic plasticity as therapy for neurological and psychiatric disorders.Molecular psychiatry · 2025Review
- Presymptomatic targeted circuit manipulation for ameliorating Huntington's disease pathogenesis.iScience · 2025Article
- Transcriptomic Regulation by Astrocytic m6A Methylation in the mPFC.Genes to cells : devoted to molecular & cellular mechanisms · 2025Article
- Effects of mFrontiers in aging neuroscience · 2025Article
- Single-cell mNature neuroscience · 2024Article
- m6A/m1A/m5C-Associated Methylation Alterations and Immune Profile in MDD.Molecular neurobiology · 2024Article
- RNA methylation in neurodevelopment and related diseases.Acta biochimica et biophysica Sinica · 2024Review
- Presymptomatic Targeted Circuit Manipulation for Ameliorating Huntington's Disease Pathogenesis.bioRxiv : the preprint server for biology · 2024Article
- METTL14-mediated upregulation of lncRNA HOTAIR represses PP1α expression by promoting H3K4me1 demethylation in oxycodone-treated mice.CNS neuroscience & therapeutics · 2024Article
- Astrocytic ALKBH5 in stress response contributes to depressive-like behaviors in mice.Nature communications · 2024Article
- Advances in brain epitranscriptomics research and translational opportunities.Molecular psychiatry · 2024Review
38 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Jessica L KorandaDepartment of Neurobiology, University of Chicago, Chicago, IL 60637, USA.
Lou DoreDepartment of Chemistry, University of Chicago, Chicago, IL 60637, USA.
Hailing ShiDepartment of Chemistry, University of Chicago, Chicago, IL 60637, USA.
Meera J PatelCommittee on Neurobiology, University of Chicago, Chicago, IL 60637, USA.
Lee O VaasjoDepartment of Neurobiology, University of Chicago, Chicago, IL 60637, USA.
Meghana N RaoDepartment of Neurobiology, University of Chicago, Chicago, IL 60637, USA.
Kai ChenDepartment of Chemistry, University of Chicago, Chicago, IL 60637, USA.
Zhike LuDepartment of Chemistry, University of Chicago, Chicago, IL 60637, USA.
Yangtian YiDepartment of Neurobiology, University of Chicago, Chicago, IL 60637, USA.
Wanhao ChiGenetics, Genomics, and Systems Biology, University of Chicago, Chicago, IL 60637, USA.
Chuan HeDepartment of Chemistry, University of Chicago, Chicago, IL 60637, USA. Electronic address: chuanhe@uchicago.edu.
Xiaoxi ZhuangDepartment of Neurobiology, University of Chicago, Chicago, IL 60637, USA; Committee on Neurobiology, University of Chicago, Chicago, IL 60637, USA. Electronic address: xzhuang@uchicago.edu.
University of Chicago · USUniversity of Illinois Chicago · US
Funding
Transcriptome-wide base-resolution sequencing of pseudouridine in human normal and AD brain tissues-CEGS Admin supplement 2020-2021RM1HG008935 · NHGRI · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2016 to 2025
$24.4MTranslational models of neurodevelopmental epigenetics and disease using human iPSCsP01NS097206 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI HE, CHUAN · 2016 to 2020
$4.3MIntegrative Training in the Neurobiology of Addictive BehaviorsT32DA043469 · NIDA · UNIVERSITY OF CHICAGO · PI Donald Hedeker, Xiaoxi Zhuang · 2017 to 2026
$3.8MRNA methylation in synaptic plasticity and drug-seekingR01DA043361 · NIDA · UNIVERSITY OF CHICAGO · PI ZHUANG, XIAOXI · 2017 to 2021
$2.8MRecognition and mechanism of N6-methyl adenosine modificationsR01GM113194 · NIGMS · UNIVERSITY OF CHICAGO · PI PAN, TAO · 2015 to 2022
$2.5MTraining in Emerging Multidisciplinary Approaches to Mental Health and DiseaseT32MH020065 · NIMH · UNIVERSITY OF CHICAGO · PI NICOLAE, DAN LIVIU, RZHETSKY, ANDREY · 2002 to 2017
$2.3MBase-resolution sequencing of m6A in RNAR01HG008688 · NHGRI · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2015 to 2017
$1.3MDynamics of m6A methylated Arc mRNAR21NS103159 · NINDS · UNIVERSITY OF CHICAGO · PI DELGADO, JARY YAMIR, ZHUANG, XIAOXI · 2018 to 2019
$446kNHGRI NIH HHS R01 HG008688NHGRI NIH HHS RM1 HG008935NIDA NIH HHS R01 DA043361NIDA NIH HHS T32 DA043469NIGMS NIH HHS R01 GM113194NIMH NIH HHS T32 MH020065NINDS NIH HHS P01 NS097206NINDS NIH HHS R21 NS103159
Abstract
N
Indexed as
AnimalsCorpus StriatumEpigenesis, GeneticFemaleGene Expression ProfilingLearningMaleMaze LearningMethyltransferasesMiceMice, Inbred C57BLMice, TransgenicOrgan Culture TechniquesMethyltransferasesMettl14 protein, mouseepitranscriptomem(6)AMettl14mRNA methylationN(6)-methyladenosinestriatal learningstriatonigral neuronsstriatopallidal neuronstranslational regulation
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.