ReviewExpert review of respiratory medicine2018
The effect of obesity on lung function.
Review in Expert review of respiratory medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 451 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigation of the Effects of Different Obesity Levels on the Respiratory System: In Our Study, Besides the Effect of Obesity on the Respiratory System, Many Different Parameters Related to Health Will be Compared.
Effects of Senobi Breathing Exercises on Body Fat, Lung Functions and Depression in Obese Women
Physiological Impact of Surgical Mask and N95 Mask on Obese Operating Room Staff:A Randomized-Controlled Cross-Over Trial
The Metabolic and Respiratory Effects of Intermittent Hypoxia-hyperoxia Therapy in Obese Patients Within the Complex Management of Medical Rehabilitation
Who cites it
451 citing papers in PubMed, 6 syntheses or guidelines pooled it, 852 citations in OpenAlex.
- Laparoscopic versus open repair for umbilical hernia: outcomes and complications.Hernia : the journal of hernias and abdominal wall surgery · 2026Pooled it
- Association between body mass index and prognosis in interstitial lung disease: systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Association between hypertension and impaired lung function among adults: A systematic review and meta-analysis.PloS one · 2026Pooled it
- Host factors associated with respiratory particle emission and virus presence within respiratory particles: a systematic review.Frontiers in microbiology · 2025Pooled it
- Obesity as a Risk Factor for Complications and Mortality in Individuals with SARS-CoV-2: A Systematic Review.Nutrients · 2024Pooled it
- Thoracostomy tube withdrawal during latter phases of expiration or inspiration: a systematic review and meta-analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023Pooled it
- Effect of intermittent recruitment manoeuvre combined with PEEP on postoperative atelectasis in obese patients: a randomized controlled trial.BMC anesthesiology · 2026Trial
- Observational
- Trends in comorbidities and multimorbidity among adults with recently diagnosed diabetes: United States, 1999-2023.Diabetes research and clinical practice · 2026Article
- Inflammasomes in respiratory diseases: from disease pathogenesis to drug development and use of multi-omics.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- Metabolic Syndrome-Associated Pulmonary Lipid and Iron Accumulation and Alterations in TLR4/NF-κB Signaling and Ferroptosis-Regulatory Proteins Are Attenuated by Resveratrol Plus Quercetin in Rats.Current issues in molecular biology · 2026Article
- Optimizing cardiac surgery outcomes in morbid obesity: Surgical, anesthetic, perfusion, and critical care considerations, a narrative review.The journal of extra-corporeal technology · 2026Review
- Article
- Prevalence and associated factors of cough syncope in patients with chronic cough: a multicentre prospective study.ERJ open research · 2026Article
- Oxygenaging: A Physiological Framework for Geroscience.Aging cell · 2026Review
- BMI threshold associates with increased 30-day complications after total thyroidectomy surgery.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Relationship between asthma, obesity and other comorbidities: the Australasian Severe Asthma Registry.Respiratory research · 2026Article
- Association Between Serum Leptin Concentrations and Disease Severity Across Airway Disease Phenotypes: A Single-Center Retrospective Observational Study.Diseases (Basel, Switzerland) · 2026Article
- Article
- Associations Between Opioid Timing and Postoperative Desaturation Burden Following Metabolic Bariatric Surgery.Obesity surgery · 2026Article
391 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
introductionThere is a major epidemic of obesity, and many obese patients suffer with respiratory symptoms and disease. The overall impact of obesity on lung function is multifactorial, related to mechanical and inflammatory aspects of obesity. Areas covered: Obesity causes substantial changes to the mechanics of the lungs and chest wall, and these mechanical changes cause asthma and asthma-like symptoms such as dyspnea, wheeze, and airway hyperresponsiveness. Excess adiposity is also associated with increased production of inflammatory cytokines and immune cells that may also lead to disease. This article reviews the literature addressing the relationship between obesity and lung function, and studies addressing how the mechanical and inflammatory effects of obesity might lead to changes in lung mechanics and pulmonary function in obese adults and children. Expert commentary: Obesity has significant effects on respiratory function, which contribute significantly to the burden of respiratory disease. These mechanical effects are not readily quantified with conventional pulmonary function testing and measurement of body mass index. Changes in mediators produced by adipose tissue likely also contribute to altered lung function, though as of yet this is poorly understood.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.