Evidence map›Paper›PMID 30056592›Full record

ArticleInternational journal of computer assisted radiology and surgery2019

Combined OCT distance and FBG force sensing cannulation needle for retinal vein cannulation: in vivo animal validation.

M Ourak, J Smits, L Esteveny, G Borghesan, A Gijbels, L Schoevaerdts, Y Douven, J Scholtes, E Lankenau, T Eixmann and 12 more

Abstract readValidation Study
PubMed Publisher
In one paragraph

Article in International journal of computer assisted radiology and surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Motion Compensation and Adaptive Force Control via iOCT-FBG Sensor Fusion for Robotic Subretinal Injection.IEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation · 2026
    Article
  2. Review
  3. Deep Learning-Enhanced Robotic Subretinal Injection with Real-Time Retinal Motion Compensation.IEEE International Conference on Automation Science and Engineering (CASE) : [proceedings]. IEEE Conference on Automation Science and Engineering · 2025
    Article
  4. Article
  5. Review
  6. A Review of Recent Advancements in Sensor-Integrated Medical Tools.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  7. Article
  8. Robotic Assistance for Intraocular Microsurgery: Challenges and Perspectives.Proceedings of the IEEE. Institute of Electrical and Electronics Engineers · 2022
    Article
  9. Article
  10. Article
  11. A Comparison of Manual and Robot Assisted Retinal Vein Cannulation in Chicken Chorioallantoic Membrane.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2020
    Article
  12. Autonomously Navigating a Surgical Tool Inside the Eye by Learning from Demonstration.IEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation · 2020
    Article
  13. Fiber optical shape sensing of flexible instruments for endovascular navigation.International journal of computer assisted radiology and surgery · 2019
    Article
  14. Dual-Stiffness Force-Sensing Cannulation Tool for Retinal Microsurgery.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2019
    Article
  15. Autonomous Needle Navigation in Retinal Microsurgery: Evaluation inIEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation
    Article
  16. Exploring An External Approach to Subretinal Drug Delivery via Robot Assistance and B-Mode OCT.IEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation
    Article
  17. Towards Bimanual Vein Cannulation: Preliminary Study of a Bimanual Robotic System With a Dual Force Constraint Controller.IEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

M OurakUniversity of Leuven, Leuven, Belgium. mouloud.ourak@kuleuven.be.ORCID http://orcid.org/0000-0003-4885-8965
J SmitsUniversity of Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-6450-3796
L EstevenyUniversity of Leuven, Leuven, Belgium.
G BorghesanUniversity of Leuven, Leuven, Belgium.
A GijbelsUniversity of Leuven, Leuven, Belgium.
L SchoevaerdtsUniversity of Leuven, Leuven, Belgium.
Y DouvenEindhoven University of Technology, Eindhoven, The Netherlands.
J ScholtesEindhoven University of Technology, Eindhoven, The Netherlands.
E LankenauOptoMedical Technologies GmbH, Lübeck, Germany.
T EixmannMedical Laser Center Lübeck GmbH, Lübeck, Germany.
H Schulz-HildebrandtMedical Laser Center Lübeck GmbH, Lübeck, Germany.
G HüttmannMedical Laser Center Lübeck GmbH, Lübeck, Germany.
M KozlovszkyAustrian Center for Medical Innovation and Technology Gmbh, Neustadt, Austria.
G KronreifAustrian Center for Medical Innovation and Technology Gmbh, Neustadt, Austria.
K WillekensUniversity Hospitals Leuven, Leuven, Belgium.
P StalmansUniversity Hospitals Leuven, Leuven, Belgium.
K FaridpooyaThe Rotterdam Eye Hospital, Rotterdam, The Netherlands.
M CeredaThe Eye Clinic, University of Milan, Milan, Italy.
A GianiThe Eye Clinic, University of Milan, Milan, Italy.
G StaurenghiThe Eye Clinic, University of Milan, Milan, Italy.
D ReynaertsUniversity of Leuven, Leuven, Belgium.
E B Vander PoortenUniversity of Leuven, Leuven, Belgium.

Funding

Fonds Wetenschappelijk Onderzoek (BE) 1S41517NHorizon 2020 Framework Programme 645331
6 · The paper itself

Abstract

purposeRetinal vein cannulation is an experimental procedure during which a clot-dissolving drug is injected into an obstructed retinal vein. However, due to the fragility and minute size of retinal veins, such procedure is considered too risky to perform manually. With the aid of surgical robots, key limiting factors such as: unwanted eye rotations, hand tremor and instrument immobilization can be tackled. However, local instrument anatomy distance and force estimation remain unresolved issues. A reliable, real-time local interaction estimation between instrument tip and the retina could be a solution. This paper reports on the development of a combined force and distance sensing cannulation needle, and its experimental validation during in vivo animal trials.

methodsTwo prototypes are reported, relying on force and distance measurements based on FBG and OCT A-scan fibres, respectively. Both instruments provide an 80 [Formula: see text] needle tip and have outer shaft diameters of 0.6 and 2.3 mm, respectively.

resultsBoth prototypes were characterized and experimentally validated ex vivo. Then, paired with a previously developed surgical robot, in vivo experimental validation was performed. The first prototype successfully demonstrated the feasibility of using a combined force and distance sensing instrument in an in vivo setting.

conclusionThe results demonstrate the feasibility of deploying a combined sensing instrument in an in vivo setting. The performed study provides a foundation for further work on real-time local modelling of the surgical scene. This paper provides initial insights; however, additional processing remains necessary.

Indexed as

AnimalsCatheterizationHumansMicromanipulationModels, AnimalNeedlesRetinal VeinRetinal Vein OcclusionRobotic Surgical ProceduresSwineTomography, Optical CoherenceCannulation needleFibre Bragg gratingOptical coherence tomographyRetinal vein cannulationSurgical robotics

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.