ArticleEuropean journal of clinical pharmacology2018
Barriers and facilitators of appropriate vancomycin use: prescribing context is key.
Article in European journal of clinical pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Understanding antibiotic prescribing in the inpatient setting: a synthesis of evidence on determinants and interventions.Antimicrobial resistance and infection control · 2026Article
- Pilot phase clinical trial of a wearable, electrochemical aptamer-based patch for continuous drug concentration measurement.Nature biotechnology · 2026Article
- Model-informed precision dosing of vancomycin in clinical practice: an intervention development study.International journal of clinical pharmacy · 2025Article
- Measuring and improving the timeliness of vancomycin therapeutic drug monitoring and potential patient safety impacts.Exploratory research in clinical and social pharmacy · 2024Article
- Awareness, perception, and barriers of healthcare providers toward the revised consensus guideline for therapeutic monitoring of vancomycin.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023Article
- Impact of Pharmacist-Led Multidisciplinary Team to Attain Targeted Vancomycin Area under the Curved Monitoring in a Tertiary Care Center in Thailand.Antibiotics (Basel, Switzerland) · 2023Article
- Vancomycin prescribing and therapeutic drug monitoring: Challenges of real clinical practice.PloS one · 2023Article
- Would they accept it? An interview study to identify barriers and facilitators to user acceptance of a prescribing advice service.BMC health services research · 2022Article
- Therapeutic drug monitoring in oncology - What's out there: A bibliometric evaluation on the topic.Frontiers in oncology · 2022Article
- Vancomycin dosing and therapeutic drug monitoring practices: guidelines versus real-life.International journal of clinical pharmacy · 2021Article
- Vancomycin: Audit of American guideline-based intermittent dose administration with focus on overweight patients.British journal of clinical pharmacology · 2020Article
- Dosing errors of empirical antibiotics in critically ill patients with severe sepsis or septic shock: A prospective observational study.International journal of health sciencesReview
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeAudit studies reveal frequent non-compliance with dosing and monitoring guidelines for vancomycin. This study aimed to qualitatively explore the barriers and facilitators of compliance with vancomycin dosing and monitoring guidelines.
methodsInterviews were conducted with 16 prescribers in a large tertiary teaching hospital in Sydney, Australia. Questions explored knowledge, attitudes, and perceived complexities associated with vancomycin use. Interviews were analysed using thematic analysis.
resultsPrescribers reported utilising vancomycin guidelines, citing familiarity with guidelines, a positive perception of guidelines, awareness of poor guideline compliance, and assistance from specialist staff as facilitators of the uptake of guideline recommendations. Barriers existing within the prescribing environment such as the prescribing culture, a lack of time, and poor communication and coordination of therapeutic drug monitoring processes were identified as hindrances to guideline compliance.
conclusionsThe provision of guidelines may not be sufficient in ensuring appropriate prescribing and monitoring of vancomycin when barriers relating to the prescribing environment exist. Developing interventions targeted toward these barriers, such as having dedicated phlebotomists for vancomycin blood sampling, fostering better handover processes, and educating staff on poorly understood aspects of guidelines, is likely to improve the uptake of guideline recommendations for vancomycin and other medications requiring therapeutic drug monitoring.
Indexed as
Identifiers
30056569What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.