ArticlePediatric surgery international2018
Trends in incidence and outcomes of gastroschisis in the United States: analysis of the national inpatient sample 2010-2014.
Article in Pediatric surgery international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 43 citations in OpenAlex.
- Temporal and spatial trends in isolated gastroschisis: a population-based study in a middle-income setting.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026Article
- Septo-optic dysplasia and gastroschisis: trends in birth prevalence and association with maternal age.European journal of pediatrics · 2025Article
- Management of gastroschisis in an extremely low birth weight infant: report of a case.Surgical case reports · 2024Article
- County-Level Atrazine Use and Gastroschisis.JAMA network open · 2024Article
- Longitudinal growth of children born with gastroschisis or omphalocele.European journal of pediatrics · 2023Article
- Gastroschisis or exomphalos? An unusual abdominal defect.BMJ case reports · 2021Article
- Left congenital diaphragmatic hernia and gastroschisis in a term male infant.BMJ case reports · 2021Article
- Predictors of Length of Stay and Cost of Hospitalization of Neonatal Abstinence Syndrome in the United States.Cureus · 2021Article
- Regional variation in gastroschisis: a nationwide database review of demographics and outcomes.Pediatric surgery international · 2021Article
- Trends in prevalence and spatiotemporal distribution of gastroschisis in Arkansas, 1998-2015.Birth defects research · 2020Article
- Relationship between volume and outcome for gastroschisis: a systematic review protocol.Systematic reviews · 2020Article
- Influence of birthplace on gastroschisis outcomes in a state in the southeastern region of Brazil.Jornal de pediatriaArticle
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeGastroschisis is a severe congenital anomaly associated with a significant morbidity and mortality. There are limited temporal trend data on incidence, mortality, length of stay, and hospital cost of gastroschisis. Our aim was to study these temporal trends using the National Inpatient Sample (NIS).
methodsWe identified all neonatal admissions with a diagnosis of gastroschisis within the NIS from 2010 through 2014. We limited admission age to ≤ 28 days and excluded all those transferred to other hospitals. We estimated gastroschisis incidence, mortality, length of hospital stay, and cost of hospitalization. For continuous variables, trends were analyzed using survey regression. Cochrane-Armitage trend test was used to analyze trends for categorical variables. P < 0.05 was considered as significant.
resultsThe incidence of gastroschisis increased from 4.5 to 4.9/10,000 live births from 2010 through 2014 (P = 0.01). Overall mortality was 3.5%, median length of stay was 35 days (95% CI 26-55 days), and median cost of hospitalization was $75,859 (95% CI $50,231-$122,000). After adjusting for covariates, there was no statistically significant change in mortality (OR = 1.13; 95% CI 0.87-1.48), LOS (β = - 2.1 ± 3.5; 95% CI - 9.0 to 4.8) and hospital cost (β = - 2.137 ± 10.813; 95% CI - 23,331 to 19,056) with each calendar year increase on multivariate logistic regression analysis.
conclusionThe incidence of neonates with gastroschisis increased between 2010 and 2014. Incidence was highest in the West. No difference in mortality and resource utilization was observed.
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