Evidence map›Paper›PMID 30056275›Full record

ReviewCurrent opinion in genetics & development2018

Inference of population history using coalescent HMMs: review and outlook.

Jeffrey P Spence, Matthias Steinrücken, Jonathan Terhorst, Yun S Song

Abstract readReview
In one paragraph

Review in Current opinion in genetics & development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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  7. Computational Genomics and Its Applications to Anthropological Questions.American journal of biological anthropology · 2024
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  9. Article
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  13. Exact Decoding of a Sequentially Markov Coalescent Model in Genetics.Journal of the American Statistical Association · 2024
    Article
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jeffrey P SpenceComputational Biology Graduate Group, University of California, Berkeley, United States.
Matthias SteinrückenDepartment of Ecology and Evolution, University of Chicago, United States.
Jonathan TerhorstDepartment of Statistics, University of Michigan, United States.
Yun S SongComputer Science Division and Department of Statistics, University of California, Berkeley, United States; Chan Zuckerberg Biohub, San Francisco, United States. Electronic address: yss@berkeley.edu.

Funding

Mathematical Models and Statistical Methods for Large-Scale Population GenomicsR01GM094402 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI SONG, YUN S · 2010 to 2018
$2.2M
NIGMS NIH HHS R01 GM094402
6 · The paper itself

Abstract

Studying how diverse human populations are related is of historical and anthropological interest, in addition to providing a realistic null model for testing for signatures of natural selection or disease associations. Furthermore, understanding the demographic histories of other species is playing an increasingly important role in conservation genetics. A number of statistical methods have been developed to infer population demographic histories using whole-genome sequence data, with recent advances focusing on allowing for more flexible modeling choices, scaling to larger data sets, and increasing statistical power. Here we review coalescent hidden Markov models, a powerful class of population genetic inference methods that can utilize linkage disequilibrium information effectively. We highlight recent advances, give advice for practitioners, point out potential pitfalls, and present possible future research directions.

Indexed as

Evolution, MolecularGenetics, PopulationGenome, HumanHumansMarkov ChainsSelection, GeneticWhole Genome Sequencing

Identifiers

PMID30056275
PMCPMC6296859

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.