Evidence map›Paper›PMID 30055832›Full record

ArticleTrends in neurosciences2018

A dLight-ful New View of Neuromodulation.

Caitlin V Cosme, Gates K Palissery, Talia N Lerner

Abstract readComment
In one paragraph

Article in Trends in neurosciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The prediction-error hypothesis of schizophrenia: new data point to circuit-specific changes in dopamine activity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Review
  7. Evaluation of electrochemical methods for tonic dopamine detectionTrends in analytical chemistry : TRAC · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Caitlin V CosmeDepartment of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Gates K PalisseryDepartment of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Talia N LernerDepartment of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. Electronic address: talia.lerner@northwestern.edu.

Funding

Contributions of Parallel Nigrostriatal Dopamine Circuits to Reward Learning and Habit FormationR00MH109569 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LERNER, TALIA NEWCOMBE · 2017 to 2019
$874k
NIMH NIH HHS R00 MH109569
6 · The paper itself

Abstract

Neuromodulators such as dopamine can transform neural circuit function, but the mechanisms underlying such transformations are incompletely understood. A recent study introduced dLight1, a genetically encoded fluorescent dopamine indicator. dLight1 allows the optical measurement of dopamine sensed by isolated target circuits with high spatiotemporal resolution and has unique advantages for the study of neuromodulatory mechanisms.

Indexed as

DopamineNeuronsNeurotransmitter AgentsDopamineNeurotransmitter Agentsdopaminegenetically encoded indicatorsimagingneuromodulation

Identifiers

PMID30055832
PMCPMC6519934

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.