ArticleBMC genomics2018
Transcriptomic analysis reveals candidate genes regulating development and host interactions of Colletotrichum fructicola.
Article in BMC genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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Who cites it
34 citing papers in PubMed, 67 citations in OpenAlex.
- Molecular insights and integrated management of Glomerella leaf spot in apple.Horticulture research · 2026Review
- Elucidation of the Biological Function and Early-Infection Cell Cycle Regulatory Mechanism of Avocado-InfectingFoods (Basel, Switzerland) · 2026Article
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- Plant Pathogenic and EndophyticMicroorganisms · 2025Review
- Dominant foliar endophytes influence soybean yield and transcriptome.FEMS microbiology ecology · 2025Article
- Decoding Pecan's Fungal Foe: A Genomic Insight intoJournal of fungi (Basel, Switzerland) · 2025Article
- The dark side of avocados: a review of anthracnose and stem-end rot in postharvest fruit.Frontiers in microbiology · 2025Review
- Exploring the infection strategy ofFrontiers in plant science · 2025Article
- Apple Bitter Rot: Biology, Ecology, Omics, Virulence Factors, and Management of Causal Colletotrichum Species.Molecular plant pathology · 2025Review
- Quantification of the fungal pathogen Didymella segeticola in Camellia sinensis using a DNA-based qRT-PCR assay.Plant methods · 2024Article
- Extracellular perception of multiple novel core effectors from the broad host-range pear anthracnose pathogenHorticulture research · 2024Article
- Genome comparisons reveal accessory genes crucial for the evolution of apple Glomerella leaf spot pathogenicity in Colletotrichum fungi.Molecular plant pathology · 2024Article
- Genome evolution and transcriptome plasticity is associated with adaptation to monocot and dicot plants in Colletotrichum fungi.GigaScience · 2024Article
- Histological and transcriptomic insights into the interaction between grapevine andFrontiers in plant science · 2024Article
- A fungal CFEM-containing effector targets NPR1 regulator NIMIN2 to suppress plant immunity.Plant biotechnology journal · 2024Article
- Genome Resources for the Colletotrichum gloeosporioides Species Complex: 13 Tree Endophytes from the Neotropics and Paleotropics.Microbiology resource announcements · 2023Article
- Selection and validation of reference genes for normalizing qRT‒PCR gene expression studies inFrontiers in plant science · 2023Article
- Effector Sntf2 Interacted with Chloroplast-Related Protein Mdycf39 Promoting the Colonization ofInternational journal of molecular sciences · 2022Article
- Comparative transcriptome analysis reveals significant differences in gene expression between pathogens of apple Glomerella leaf spot and apple bitter rot.BMC genomics · 2022Article
- Recent progress on harm, pathogen classification, control and pathogenic molecular mechanism of anthracnose of oil-tea.Frontiers in microbiology · 2022Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundColletotrichum is a fungal genus in Ascomycota that contain many plant pathogens. Among all Colletotrichum genomes that have been sequenced, C. fructicola contains the largest number of candidate virulence factors, such as plant cell wall degrading enzymes, secondary metabolite (SM) biosynthetic enzymes, secreted proteinases, and small secreted proteins. Systematic analysis of the expressional patterns of these factors would be an important step toward identifying key virulence determinants.
resultsIn this study, we obtained and compared the global transcriptome profiles of four types of infection-related structures: conidia, appressoria, infected apple leaves, and cellophane infectious hyphae (bulbous hyphae spreading inside cellophane) of C. fructicola. We also compared the expression changes of candidate virulence factors among these structures in a systematic manner. A total of 3189 genes were differentially expressed in at least one pairwise comparison. Genes showing in planta-specific expressional upregulations were enriched with small secreted proteins (SSPs), cytochrome P450s, carbohydrate-active enzymes (CAZYs) and secondary metabolite (SM) synthetases, and included homologs of several known candidate effectors and one SM gene cluster specific to the Colletotrichum genus. In conidia, tens of genes functioning in triacylglycerol biosynthesis showed coordinately expressional upregulation, supporting the viewpoint that C. fructicola builds up lipid droplets as energy reserves. Several phosphate starvation responsive genes were coordinately up-regulated during early plant colonization, indicating a phosphate-limited in planta environment immediately faced by biotrophic infectious hyphae.
conclusionThis study systematically analyzes the expression patterns of candidate virulence genes, and reveals biological activities related to the development of several infection-related structures of C. fructicola. Our findings lay a foundation for further dissecting infection mechanisms in Colletotrichum and identifying disease control targets.
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