Evidence map›Paper›PMID 30055168›Full record

ArticleChest2018

Characteristics and Health-care Utilization History of Patients With Bronchiectasis in US Medicare Enrollees With Prescription Drug Plans, 2006 to 2014.

Emily Henkle, Benjamin Chan, Jeffrey R Curtis, Timothy R Aksamit, Charles L Daley, Kevin L Winthrop

Abstract read
PubMed Publisher
In one paragraph

Article in Chest, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 92 citations in OpenAlex.

  1. Pooled it
  2. A systematic literature review of the clinical and socioeconomic burden of bronchiectasis.European respiratory review : an official journal of the European Respiratory Society · 2024
    Pooled it
  3. Trial
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  5. Article
  6. Review
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  8. Review
  9. Review
  10. Review
  11. Article
  12. ERJ open research · 2025
    Article
  13. Review
  14. Article
  15. Epidemiology of bronchiectasis.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  16. Review
  17. Article
  18. Article
  19. To Boldly Go into Molecular Endotypes of Bronchiectasis Exacerbations.American journal of respiratory and critical care medicine · 2024
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Emily HenkleOHSU-PSU School of Public Health, Portland, OR. Electronic address: henkle@ohsu.edu.
Benjamin ChanOHSU-PSU School of Public Health, Portland, OR.
Jeffrey R CurtisDivision of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham AL.
Timothy R AksamitPulmonary Disease and Critical Care Medicine, Mayo Clinic, Rochester, MN.
Charles L DaleyDivision of Mycobacterial and Respiratory Infections, National Jewish Health, Denver, CO.
Kevin L WinthropOHSU-PSU School of Public Health, Portland, OR.
Mayo Clinic in Florida · USNational Jewish Health · USOregon Health & Science University · USUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBronchiectasis is an increasingly common chronic inflammatory airway disease. There is an urgent need to understand the epidemiology of bronchiectasis in older adults. We describe the prevalence and characteristics of patients with bronchiectasis within the US Medicare population.

methodsAmong the 40% of Medicare enrollees with prescription drug plans from 2006 to 2014, we identified patients ≥ 65 years of age with bronchiectasis by International Classification of Diseases, Ninth Revision, Clinical Modification claims (494.0 or 494.1) from a pulmonologist and no claim for cystic fibrosis. We calculated the prevalence from 2012 to 2014. Incident or newly diagnosed patients were those enrolled in Medicare at least 12 months prior to the first bronchiectasis diagnosis. We described clinical and health-care utilization characteristics for this cohort during the prior 12-month (baseline) period, and explored differences between those with and without a COPD diagnosis.

resultsWe identified 252,362 patients with bronchiectasis meeting all eligibility criteria. The average annual prevalence from 2012 to 2014 was 701 per 100,000 persons. Newly diagnosed patients were a mean age of 76 years, predominately women (65%), and predominately white, non-Hispanic (84%). During the baseline period, 12% were hospitalized for respiratory infections. Fifty-one percent had a dual diagnosis of COPD. Newly diagnosed patients with bronchiectasis and COPD had significantly different characteristics and utilization, for example were more likely hospitalized for respiratory infections during the baseline period (16% vs 7%) and to have a smoking history (46% vs 17%) compared with those without a dual COPD diagnosis, respectively.

conclusionsWe confirmed a high prevalence of bronchiectasis in the United States and significant heterogeneity in patients with bronchiectasis with and without COPD that should be further explored.

Indexed as

BronchiectasisAgedFemaleHospitalizationHumansInsurance Claim ReviewMaleMedicarePatient Acceptance of Health CarePrevalencePulmonary Disease, Chronic ObstructiveRespiratory System AgentsUnited StatesWhite PeopleRespiratory System AgentsbronchiectasisCOPDepidemiologyMedicare

Identifiers

PMID30055168
OpenAlexW2883063895

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.