Evidence map›Paper›PMID 30054805›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2018

Time to diagnosis of pediatric brain tumors: a report from the Pediatric Hematology and Oncology Center in Rabat, Morocco.

Fatima Zahra Boutahar, Sarra Benmiloud, Maria El Kababri, Amina Kili, Mohamed El Khorassani, Nazik Allali, Mohamed Khattab, Ibrahim Qaddoumi, Laila Hessissen

Open access · greenAbstract read
In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Delay in the diagnosis of pediatric central nervous system tumors: data from a single tertiary care center.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
  4. Article
  5. Article
  6. Unlocking delays: revealing barriers to early diagnosis of childhood central nervous system tumors in an upper-middle-income country.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Presenting symptoms and time to diagnosis for Pediatric Central Nervous System Tumors in Qatar: a report from Pediatric Neuro-Oncology Service in Qatar.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Article
  14. Patterns, treatments, and outcomes of pediatric central nervous system tumors in Sudan: a single institution experience.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Fatima Zahra BoutaharMedical School of Rabat-Morocco, Rabat, Morocco.
Sarra BenmiloudDepartment of Pediatric Oncology, University Hassan II Fès, Fez, Morocco.
Maria El KababriPediatric Hematology and Oncology Center, University Mohamed V Rabat, Ibn Rochd Avenue, 6542, Rabat, BP, Morocco.
Amina KiliPediatric Hematology and Oncology Center, University Mohamed V Rabat, Ibn Rochd Avenue, 6542, Rabat, BP, Morocco.
Mohamed El KhorassaniPediatric Hematology and Oncology Center, University Mohamed V Rabat, Ibn Rochd Avenue, 6542, Rabat, BP, Morocco.
Nazik AllaliDepartment of Pediatric Radiology, University Mohamed V Rabat, Rabat, Morocco.
Mohamed KhattabPediatric Hematology and Oncology Center, University Mohamed V Rabat, Ibn Rochd Avenue, 6542, Rabat, BP, Morocco.
Ibrahim QaddoumiDepartment of Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN, USA.
Laila HessissenPediatric Hematology and Oncology Center, University Mohamed V Rabat, Ibn Rochd Avenue, 6542, Rabat, BP, Morocco. lailahsn@gmail.com.ORCID 0000-0002-3322-273X
Mohammed V University · MACentre Hospitalier Universitaire Hassan II · MAÉcole des Hautes Études Commerciales · MASt. Jude Children's Research Hospital · US

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
NCI NIH HHS P30 CA021765
6 · The paper itself

Abstract

objectiveDelayed diagnosis of pediatric brain tumors is known to occur worldwide but is not well studied in developing countries. Here, we examined the extent of delayed pediatric brain tumor diagnoses in Rabat, Morocco, and consider its potential causes and possible solutions.

methodsWe conducted a survey and interviews of the parents of children who were admitted to the Department of Hematology and Pediatric Oncology of Rabat Children's Hospital from January 1, 2016 to June 30, 2016.

resultsThe families of 27 patients (14 girls and 13 boys) participated in the survey and interview. The median patient age was 7 years (range, 1-15 years). The most common presenting symptoms were vomiting (n = 18) and headache (n = 17). The tumor locations were supratentorial in 13 cases and infratentorial in 14 cases. The median time to diagnosis was 2 months (range, 0.25-20 months). The longest times to diagnosis occurred in children older than 5 years and in patients with supratentorial tumors or low-grade glioma. We did not observe any differences in the time to diagnosis according to sex, socioeconomic status, or urban or rural origin.

conclusionsDelayed diagnosis of pediatric brain tumors is a universal problem, evidenced by many studies in different countries. We propose that a paradigm shift in medical curricula addressing the delayed diagnosis of pediatric brain tumors should occur in medical schools and clinical training programs.

Indexed as

AdolescentBrain NeoplasmsChildChild, PreschoolDelayed DiagnosisFemaleHumansInfantMaleMoroccoBrain neoplasmsChildDelayed diagnosisIntracranial hypertension

Identifiers

PMID30054805
PMCPMC7685949
OpenAlexW2884616390

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.