Evidence map›Paper›PMID 30054554›Full record

ArticleLeukemia2018

Comment on structural basis of DUX4/IGH-driven transactivation.

Hideki Aihara, Ke Shi, John K Lee, Darko Bosnakovski, Michael Kyba

Abstract readLetter
In one paragraph

Article in Leukemia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hideki AiharaDepartment of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, 55455, USA. aihar001@umn.edu.ORCID http://orcid.org/0000-0001-7508-6230
Ke ShiDepartment of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, 55455, USA.
John K LeeDepartment of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, 55455, USA.
Darko BosnakovskiLillehei Heart Institute, University of Minnesota, Minneapolis, MN, 55455, USA.
Michael KybaLillehei Heart Institute, University of Minnesota, Minneapolis, MN, 55455, USA.ORCID http://orcid.org/0000-0002-5579-7534

Funding

Probing the Activity of DUX4 in FSHDR01AR055685 · NIAMS · UNIVERSITY OF MINNESOTA · PI Michael Kyba · 2010 to 2026
$7.0M
Structural studies of viral replication and invasionR35GM118047 · NIGMS · UNIVERSITY OF MINNESOTA · PI Hideki Aihara · 2016 to 2026
$6.3M
NIAMS NIH HHS R01 AR055685NIGMS NIH HHS R35 GM118047
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Transcriptional ActivationBinding SitesGene Expression RegulationHomeodomain ProteinsHumansProtein BindingStructure-Activity RelationshipDUX4L1 protein, humanHomeodomain Proteins

Identifiers

PMID30054554
PMCPMC6343488

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.