ArticleScientific reports2018
Types of tobacco consumption and the oral microbiome in the United Arab Emirates Healthy Future (UAEHFS) Pilot Study.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.
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Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Microbiome and One Health in GCC countries: current status, research gaps, and future directions.Frontiers in microbiology · 2026Pooled it
- Cytotoxic and Genotoxic Effects of Waterpipe on Oral Health Status: Systematic review and meta-analysis.Sultan Qaboos University medical journal · 2023Pooled it
- Influence of heat-non-burn tobacco aerosol on the microbiome of biofilm from human whole saliva bacteria in vitro.Clinical oral investigations · 2026Article
- Characteristics of Respiratory Microbiome in COPD-A Literature Review.Advances in respiratory medicine · 2026Review
- Integrative insights into the oral microbiome's role in systemic diseases: novel therapeutic strategies and future directions.Antonie van Leeuwenhoek · 2025Review
- Oral microbiome dysbiosis among cigarette smokers and smokeless tobacco users compared to non-users.Scientific reports · 2024Article
- The adolescent and young adult microbiome and its association with substance use: a scoping review.Alcohol and alcoholism (Oxford, Oxfordshire) · 2024Article
- Effect of different forms of tobacco on the oral microbiome in healthy adults: a systematic review.Frontiers in oral health · 2024Review
- A literature review addressing midwakh and e-cigarette use in the Gulf region.The Journal of the Egyptian Public Health Association · 2023Review
- Association of cigarette smoking with oral bacterial microbiota and cardiometabolic health in Chinese adults.BMC microbiology · 2023Article
- Smoking and salivary microbiota: a cross-sectional analysis of an Italian alpine population.Scientific reports · 2023Article
- The increasing importance of the oral microbiome in periodontal health and disease.Future science OA · 2023Review
- Alteration of oral bacteriome of smokeless tobacco users and their association with oral cancer.Applied microbiology and biotechnology · 2023Article
- Impact of waterpipe smoking on the salivary microbiome.Frontiers in oral health · 2023Article
- Oral microbiota dysbiosis accelerates the development and onset of mucositis and oral ulcers.Frontiers in microbiology · 2023Review
- The role of the oral microbiome in smoking-related cardiovascular risk: a review of the literature exploring mechanisms and pathways.Journal of translational medicine · 2022Review
- Smokeless tobacco consumption induces dysbiosis of oral mycobiome: a pilot study.Applied microbiology and biotechnology · 2022Article
- Citizen-science reveals changes in the oral microbiome in Spain through age and lifestyle factors.NPJ biofilms and microbiomes · 2022Article
- Dental Caries and Oral Health Status of Psychoactive Substance Abusers.International journal of environmental research and public health · 2022Article
- Supragingival microbiome alternations as a consequence of smoking different tobacco types and its relation to dental caries.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
28 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cigarette smoking alters the oral microbiome; however, the effect of alternative tobacco products remains unclear. Middle Eastern tobacco products like dokha and shisha, are becoming globally widespread. We tested for the first time in a Middle Eastern population the hypothesis that different tobacco products impact the oral microbiome. The oral microbiome of 330 subjects from the United Arab Emirates Healthy Future Study was assessed by amplifying the bacterial 16S rRNA gene from mouthwash samples. Tobacco consumption was assessed using a structured questionnaire and further validated by urine cotinine levels. Oral microbiome overall structure and specific taxon abundances were compared, using PERMANOVA and DESeq analyses respectively. Our results show that overall microbial composition differs between smokers and nonsmokers (p = 0.0001). Use of cigarettes (p = 0.001) and dokha (p = 0.042) were associated with overall microbiome structure, while shisha use was not (p = 0.62). The abundance of multiple genera were significantly altered (enriched/depleted) in cigarette smokers; however, only Actinobacillus, Porphyromonas, Lautropia and Bifidobacterium abundances were significantly changed in dokha users whereas no genera were significantly altered in shisha smokers. For the first time, we show that smoking dokha is associated to oral microbiome dysbiosis, suggesting that it could have similar effects as smoking cigarettes on oral health.
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