Evidence map›Paper›PMID 30054384›Full record

ArticleJournal of cell science2018

Integrin signaling downregulates filopodia during muscle-tendon attachment.

Benjamin Richier, Yoshiko Inoue, Ulrich Dobramysl, Jonathan Friedlander, Nicholas H Brown, Jennifer L Gallop

Open access · hybridAbstract read
In one paragraph

Article in Journal of cell science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Effects of mutant lamins on nucleo-cytoskeletal coupling inFrontiers in cell and developmental biology · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. The extracellular matrix in development.Development (Cambridge, England) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Benjamin RichierThe Gurdon Institute, Tennis Court Rd, Cambridge CB2 1QN, UK.ORCID 0000-0001-7641-8508
Yoshiko InoueThe Gurdon Institute, Tennis Court Rd, Cambridge CB2 1QN, UK.ORCID 0000-0002-9709-8600
Ulrich DobramyslThe Gurdon Institute, Tennis Court Rd, Cambridge CB2 1QN, UK.ORCID 0000-0001-9363-654X
Jonathan FriedlanderThe Gurdon Institute, Tennis Court Rd, Cambridge CB2 1QN, UK.ORCID 0000-0003-3796-9571
Nicholas H BrownThe Gurdon Institute, Tennis Court Rd, Cambridge CB2 1QN, UK.ORCID 0000-0002-8958-7017
Jennifer L GallopThe Gurdon Institute, Tennis Court Rd, Cambridge CB2 1QN, UK j.gallop@gurdon.cam.ac.uk.ORCID 0000-0002-9978-1382
University of Cambridge · GB

Funding

Cancer Research UK C6946/A14492European Research Council 281971Wellcome Trust
6 · The paper itself

Abstract

Cells need to sense their environment to ensure accurate targeting to specific destinations. This occurs in developing muscles, which need to attach to tendon cells before muscle contractions can begin. Elongating myotube tips form filopodia, which are presumed to have sensory roles, and are later suppressed upon building the attachment site. Here, we use live imaging and quantitative image analysis of lateral transverse (LT) myotubes in

Indexed as

Cell CommunicationAnimalsAnimals, Genetically ModifiedDown-RegulationDrosophilaEmbryo, NonmammalianIntegrinsMuscle DevelopmentMuscle, SkeletalPseudopodiaSignal TransductionTendonsIntegrinsActin dynamicsDrosophilaFilopodiaIntegrin signalingMuscle

Identifiers

PMID30054384
PMCPMC6127725
OpenAlexW2952632612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.