Evidence map›Paper›PMID 30054333›Full record

ArticleCancer research2018

Mucosal HPV E6/E7 Peptide Vaccination in Combination with Immune Checkpoint Modulation Induces Regression of HPV

Stephanie Dorta-Estremera, Renee L Chin, Gloria Sierra, Courtney Nicholas, Ananta V Yanamandra, Sita M K Nookala, Guojun Yang, Shail Singh, Michael A Curran, K Jagannadha Sastry

Open access · bronzeAbstract read
In one paragraph

Article in Cancer research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Trends in immunotherapy for oral squamous cell carcinoma.Cellular oncology (Dordrecht, Netherlands) · 2025
    Review
  4. Review
  5. Article
  6. Viral vector-based therapeutic HPV vaccines.Clinical and experimental medicine · 2024
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Development of HPVBiotechnology letters · 2020
    Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Stephanie Dorta-EstremeraDepartment of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Renee L ChinDepartment of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Gloria SierraDepartment of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0001-8398-7477
Courtney NicholasDepartment of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Ananta V YanamandraDepartment of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Sita M K NookalaDepartment of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Guojun YangThe University of Texas MD Anderson Cancer Center, Oncology Research for Biologics and Immunotherapy Translation, Houston, Texas, Texas.
Shail SinghDepartment of Melanoma and Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, Texas.
Michael A CurranDepartment of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
K Jagannadha SastryDepartment of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas. jsastry@mdanderson.org.
The University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

High-risk human papillomavirus (HPV)-associated squamous cell carcinomas of the oropharynx (SCCOP) are among the fastest growing cancers. After standard-of-care treatment, however, patients with HPV

Indexed as

AnimalsAntibodiesCancer VaccinesCD40 AntigensDisease Models, AnimalEpithelial CellsImmune SystemMaleMiceMice, Inbred C57BLMouth NeoplasmsMucous MembraneOncogene Proteins, ViralPalatine TonsilPapillomaviridaePapillomavirus E7 ProteinsAntibodiesCancer VaccinesCD40 AntigensE6 protein, Human papillomavirus type 16oncogene protein E7, Human papillomavirus type 16Oncogene Proteins, ViralPapillomavirus E7 ProteinsPapillomavirus VaccinesRepressor ProteinsVaccines, Subunit

Identifiers

PMID30054333
PMCPMC6524525
OpenAlexW2883846231

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.