Evidence map›Paper›PMID 30054031›Full record

ArticleBiophysical journal2018

Force-Dependent Recruitment from the Myosin Off State Contributes to Length-Dependent Activation.

Kenneth S Campbell, Paul M L Janssen, Stuart G Campbell

Open access · bronzeAbstract read
In one paragraph

Article in Biophysical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 91 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Spatial control of myosin regulatory light chain phosphorylation modulates cardiac thick filament mechanosensing.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. CaJournal of molecular and cellular cardiology · 2025
    Article
  14. Myosin-actin crossbridge independent sarcomere length induced CaJournal of molecular and cellular cardiology · 2025
    Article
  15. Review
  16. Article
  17. Frontiers in pharmacology · 2025
    Article
  18. Article
  19. Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Kenneth S CampbellDepartment of Physiology and Division of Cardiovascular Medicine, University of Kentucky, Lexington, Kentucky. Electronic address: k.s.campbell@uky.edu.
Paul M L JanssenDepartment of Physiology and Cell Biology, Ohio State University, Columbus, Ohio.
Stuart G CampbellDepartment of Biomedical Engineering, Yale University, New Haven, Connecticut.
The Ohio State University · USUniversity of Kentucky · USYale University · US

Funding

Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
Multiscale models of proprioceptive encoding to reveal mechanisms of impaired sensorimotor controlR01HD090642 · NICHD · EMORY UNIVERSITY · PI COPE, TIMOTHY C, SAWICKI, GREGORY STEPHEN · 2016 to 2025
$4.9M
Frequency-dependent modulation of cardiac myofilament function in health/diseaseR01HL113084 · NHLBI · OHIO STATE UNIVERSITY · PI JANSSEN, PAULUS ML · 2012 to 2023
$4.6M
Multiscale modeling of inherited cardiomyopathies and therapeutic interventionsU01HL133359 · NHLBI · UNIVERSITY OF KENTUCKY · PI CAMPBELL, KENNETH S, WENK, JONATHAN F · 2017 to 2021
$3.1M
NCATS NIH HHS UL1 TR001998NHLBI NIH HHS R01 HL113084NHLBI NIH HHS U01 HL133359NICHD NIH HHS R01 HD090642
6 · The paper itself

Abstract

Cardiac muscle develops more force when it is activated at longer lengths. The concentration of Ca

Indexed as

Mechanical PhenomenaAnimalsBiomechanical PhenomenaCalciumModels, BiologicalMyocardiumMyosinsPermeabilityRatsCalciumMyosins

Identifiers

PMID30054031
PMCPMC6084639
OpenAlexW2820660720

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.