Evidence map›Paper›PMID 30053423›Full record

ArticleCell2018

Whirling Platelets Away for Transfusion.

Camelia Iancu-Rubin, Ronald Hoffman, Anna Rita Migliaccio

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Whole transcriptome analysis of platelet concentrates during storage.Blood transfusion = Trasfusione del sangue · 2023
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Camelia Iancu-RubinTisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA.
Ronald HoffmanTisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA.
Anna Rita MigliaccioDepartment of Biomedical and Neuromotorial Sciences, Alma Mater University, Bologna, Italy. Electronic address: annarita.migliaccio@unibo.it.

Funding

Generation of cultured RBCs with rare phenotypes for transfusion from sources usually discarded during regular blood donationsR01HL134684 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BIEKER, JAMES J, MIGLIACCIO, ANNA RITA F · 2018 to 2021
$1.7M
NHLBI NIH HHS R01 HL134684
6 · The paper itself

Abstract

With a growing demand for platelet transfusions, large-scale ex vivo platelet production would alleviate the reliance on donors. Now, Ito et al. report that turbulence is an important physical regulator of platelet generation in vivo and can be exploited in a bioreactor to enable clinical scale production of functional platelets starting from human iPSCs.

Indexed as

Induced Pluripotent Stem CellsPlatelet TransfusionBioreactorsBlood PlateletsHumansTissue Donors

Identifiers

PMID30053423
PMCPMC6487281

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.