Evidence map›Paper›PMID 30053241›Full record

ArticleJournal of the National Cancer Institute2017

Workshop Report: Modulation of Antitumor Immune Responses by Dietary and Microbial Metabolites.

Amit Kumar, Carolyne Smith, Christian Jobin, Giorgio Trinchieri, T Kevin Howcroft, Harold Seifried, Michael Graham Espey, Roberto Flores, Young S Kim, Phillip J Daschner

Open access · hybridAbstract read
In one paragraph

Article in Journal of the National Cancer Institute, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Prognostic value of post-radiotherapy neutrophil-to-lymphocyte ratio in locally advanced nasopharyngeal carcinoma.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2020
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Amit KumarAffiliations of authors: Division of Cancer Prevention, National Cancer Institute, Bethesda, MD (AK, HS, RF, YSK); Center for Cancer Research (CS, GT) and Division of Cancer Biology (TKH, MGE, PJD), National Cancer Institute, Bethesda, MD (CS, GT); Department of Infectious Diseases and Pathology, University of Florida, Gainesville, FL (CJ).
Carolyne SmithAffiliations of authors: Division of Cancer Prevention, National Cancer Institute, Bethesda, MD (AK, HS, RF, YSK); Center for Cancer Research (CS, GT) and Division of Cancer Biology (TKH, MGE, PJD), National Cancer Institute, Bethesda, MD (CS, GT); Department of Infectious Diseases and Pathology, University of Florida, Gainesville, FL (CJ).
Christian JobinAffiliations of authors: Division of Cancer Prevention, National Cancer Institute, Bethesda, MD (AK, HS, RF, YSK); Center for Cancer Research (CS, GT) and Division of Cancer Biology (TKH, MGE, PJD), National Cancer Institute, Bethesda, MD (CS, GT); Department of Infectious Diseases and Pathology, University of Florida, Gainesville, FL (CJ).
Giorgio TrinchieriAffiliations of authors: Division of Cancer Prevention, National Cancer Institute, Bethesda, MD (AK, HS, RF, YSK); Center for Cancer Research (CS, GT) and Division of Cancer Biology (TKH, MGE, PJD), National Cancer Institute, Bethesda, MD (CS, GT); Department of Infectious Diseases and Pathology, University of Florida, Gainesville, FL (CJ).
T Kevin HowcroftAffiliations of authors: Division of Cancer Prevention, National Cancer Institute, Bethesda, MD (AK, HS, RF, YSK); Center for Cancer Research (CS, GT) and Division of Cancer Biology (TKH, MGE, PJD), National Cancer Institute, Bethesda, MD (CS, GT); Department of Infectious Diseases and Pathology, University of Florida, Gainesville, FL (CJ).
Harold SeifriedAffiliations of authors: Division of Cancer Prevention, National Cancer Institute, Bethesda, MD (AK, HS, RF, YSK); Center for Cancer Research (CS, GT) and Division of Cancer Biology (TKH, MGE, PJD), National Cancer Institute, Bethesda, MD (CS, GT); Department of Infectious Diseases and Pathology, University of Florida, Gainesville, FL (CJ).
Michael Graham EspeyAffiliations of authors: Division of Cancer Prevention, National Cancer Institute, Bethesda, MD (AK, HS, RF, YSK); Center for Cancer Research (CS, GT) and Division of Cancer Biology (TKH, MGE, PJD), National Cancer Institute, Bethesda, MD (CS, GT); Department of Infectious Diseases and Pathology, University of Florida, Gainesville, FL (CJ).
Roberto FloresAffiliations of authors: Division of Cancer Prevention, National Cancer Institute, Bethesda, MD (AK, HS, RF, YSK); Center for Cancer Research (CS, GT) and Division of Cancer Biology (TKH, MGE, PJD), National Cancer Institute, Bethesda, MD (CS, GT); Department of Infectious Diseases and Pathology, University of Florida, Gainesville, FL (CJ).
Young S KimAffiliations of authors: Division of Cancer Prevention, National Cancer Institute, Bethesda, MD (AK, HS, RF, YSK); Center for Cancer Research (CS, GT) and Division of Cancer Biology (TKH, MGE, PJD), National Cancer Institute, Bethesda, MD (CS, GT); Department of Infectious Diseases and Pathology, University of Florida, Gainesville, FL (CJ).
Phillip J DaschnerAffiliations of authors: Division of Cancer Prevention, National Cancer Institute, Bethesda, MD (AK, HS, RF, YSK); Center for Cancer Research (CS, GT) and Division of Cancer Biology (TKH, MGE, PJD), National Cancer Institute, Bethesda, MD (CS, GT); Department of Infectious Diseases and Pathology, University of Florida, Gainesville, FL (CJ).
Center for Cancer Research · USNational Cancer Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human microbiota maintains an enormous and diverse capacity to produce a diet-dependent metabolome that impacts both host tissue and microbial community homeostasis. Recent discoveries support a growing appreciation that microbial metabolites derived from bioactive foods are also important regulators of host immune and metabolic functions. To gain a better understanding of the current evidence for the roles of dietary and microbial metabolites in tumor immunity, the Division of Cancer Biology and the Division of Cancer Prevention, National Cancer Institute, cosponsored a workshop on August 31 and September 1, 2016, in Bethesda, Maryland. Workshop participants examined several lines of converging science that link nutrition, microbiology, and tumor immunology and identified key concepts and research opportunities that will accelerate our understanding of these interactions. In addition, the participants identified some of the critical gaps and research challenges that could be addressed through interdisciplinary collaborations, including future opportunities for translating new information into novel cancer prevention and treatment strategies based on targeting host immune functions that are altered by metabolite sensing pathways.

Indexed as

DietMetabolomeMicrobiotaResearch ReportEducationHumansNeoplasms

Identifiers

PMID30053241
PMCPMC6279293
OpenAlexW2613010545

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.