Evidence map›Paper›PMID 30053115›Full record

ArticleThe Journal of antimicrobial chemotherapy2018

Proposal for assignment of allele numbers for mobile colistin resistance (mcr) genes.

Sally R Partridge, Vincenzo Di Pilato, Yohei Doi, Michael Feldgarden, Daniel H Haft, William Klimke, Samir Kumar-Singh, Jian-Hua Liu, Surbhi Malhotra-Kumar, Arjun Prasad and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of antimicrobial chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
5.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 115 citations in OpenAlex.

  1. Plasmid-borneOne health (Amsterdam, Netherlands) · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Emergence of plasmid-borneMicrobiology spectrum · 2024
    Article
  7. Colistin: Lights and Shadows of an Older Antibiotic.Molecules (Basel, Switzerland) · 2024
    Review
  8. Review
  9. Article
  10. Detection ofMicroorganisms · 2024
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Frontiers in microbiology · 2023
    Review
  17. More thanFrontiers in cellular and infection microbiology · 2023
    Article
  18. Article
  19. Article
  20. Review

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 7 countries.

Sally R PartridgeCentre for Infectious Diseases and Microbiology, The Westmead Institute for Medical Research, The University of Sydney, Westmead Hospital, New South Wales, Australia.
Vincenzo Di PilatoDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Yohei DoiDivision of Infectious Diseases, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Michael FeldgardenNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.
Daniel H HaftNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.
William KlimkeNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.
Samir Kumar-SinghLaboratory of Medical Microbiology & Molecular Pathology group - Cell Biology and Histology, University of Antwerp, Antwerp, Belgium.
Jian-Hua LiuCollege of Veterinary Medicine, National Risk Assessment Laboratory for Antimicrobial Resistance of Microorganisms in Animals, South China Agricultural University, Guangzhou, China.
Surbhi Malhotra-KumarLaboratory of Medical Microbiology, Vaccine & Infectious Disease Institute, University of Antwerp, Antwerp, Belgium.
Arjun PrasadNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.
Gian Maria RossoliniDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Stefan SchwarzInstitute of Microbiology and Epizootics, Centre for Infection Medicine, Department of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany.
Jianzhong ShenBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Timothy WalshDepartment of Medical Microbiology and Infectious Disease, Cardiff University, Cardiff, UK.
Yang WangBeijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Basil Britto XavierLaboratory of Medical Microbiology, Vaccine & Infectious Disease Institute, University of Antwerp, Antwerp, Belgium.
National Center for Biotechnology Information · USUniversity of Antwerp · BEChina Agricultural University · CNAzienda Ospedaliero-Universitaria Careggi · ITCardiff University · GBFreie Universität Berlin · DESouth China Agricultural University · CNThe University of Sydney · AUUniversity of Florence · ITUniversity of Pittsburgh Medical Center · US

Funding

National Biomedical Information ServicesZIHLM200888 · NLM · NATIONAL LIBRARY OF MEDICINE · PI PALTOO, DINA · 2009 to 2025
$5200.7M
6 · The paper itself

Abstract

The initial report of the mcr-1 (mobile colistin resistance) gene has led to many reports of mcr-1 variants and other mcr genes from different bacterial species originating from human, animal and environmental samples in different geographical locations. Resistance gene nomenclature is complex and unfortunately problems such as different names being used for the same gene/protein or the same name being used for different genes/proteins are not uncommon. Registries exist for some families, such as bla (β-lactamase) genes, but there is as yet no agreed nomenclature scheme for mcr genes. The National Center for Biotechnology Information (NCBI) recently took over assigning bla allele numbers from the longstanding Lahey β-lactamase website and has agreed to do the same for mcr genes. Here, we propose a nomenclature scheme that we hope will be acceptable to researchers in this area and that will reduce future confusion.

Indexed as

AllelesGenes, MDRAnti-Bacterial AgentsBacteriabeta-LactamasesColistinDrug Resistance, BacterialEscherichia coliEscherichia coli ProteinsMicrobial Sensitivity TestsTerminology as TopicWhole Genome SequencingAnti-Bacterial Agentsbeta-LactamasesColistinEscherichia coli ProteinsMCR-1 protein, E coli

Identifiers

PMID30053115
PMCPMC6148208
OpenAlexW2884130168

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.