Evidence map›Paper›PMID 30053045›Full record

ArticleThe Journal of infectious diseases2018

Genetic Diversity of Noroviruses Circulating in a Pediatric Cohort in Bangladesh.

Martha I Nelson, Mustafa Mahfuz, Preeti Chhabra, Rashidul Haque, Jessica C Seidman, Iqbal Hossain, Monica McGrath, A M Shamsir Ahmed, Stacey Knobler, Jan Vinjé and 1 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Birth Cohort Studies Assessing Norovirus Infection and Immunity in Young Children: A Review.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Pooled it
  2. Clinical and Genotypic Features of Norovirus Enteritis in Children Complicated by Convulsions: A Retrospective Study in Kunming, China.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Homotypic and Heterotypic Protection and Risk of Reinfection Following Natural Norovirus Infection in a Highly Endemic Setting.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  8. Single-step RT-PCR assay for dual genotyping of GI and GII norovirus strains.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2021
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Martha I NelsonFogarty International Center, National Institutes of Health, Bethesda, Maryland.
Mustafa MahfuzInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka.
Preeti ChhabraCenters for Disease Control and Prevention, Atlanta, Georgia.
Rashidul HaqueInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka.
Jessica C SeidmanFogarty International Center, National Institutes of Health, Bethesda, Maryland.
Iqbal HossainInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka.
Monica McGrathFogarty International Center, National Institutes of Health, Bethesda, Maryland.
A M Shamsir AhmedInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka.
Stacey KnoblerFogarty International Center, National Institutes of Health, Bethesda, Maryland.
Jan VinjéCenters for Disease Control and Prevention, Atlanta, Georgia.
Tahmeed AhmedInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka.
International Centre for Diarrhoeal Disease Research · BDNational Institutes of Health · USCenters for Disease Control and Prevention · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noroviruses are a leading cause of diarrhea in children aged <5 years worldwide. We genotyped 88 viruses collected by active surveillance in a birth cohort of children <2 years of age in Dhaka, Bangladesh, during 2010-2013. Twenty-five of 31 (81%) established GI and GII genotypes were detected, with GII.4 as the predominant genotype (20%). Our results show that children in Bangladesh are infected with a great diversity of norovirus strains. Reinfections are common, but not with closely related genotypes. Birth cohort studies are critical to understand cross-protective immunity and advance the development of pediatric norovirus vaccines.

Indexed as

Genetic VariationBangladeshCaliciviridae InfectionsCapsid ProteinsCohort StudiesDiarrheaFecesFemaleGenotypeHumansInfantMaleNorovirusPhylogenyCapsid Proteins

Identifiers

PMID30053045
PMCPMC6217719
OpenAlexW2884105533

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.