ReviewJournal of the Pediatric Infectious Diseases Society2019
Update on Associated Risk Factors, Diagnosis, and Management of Recurrent Urinary Tract Infections in Children.
Review in Journal of the Pediatric Infectious Diseases Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07508124 (Topical Steroids to Prevent Recurrent Urinary Tract Infections in Uncircumcised Male Infants With a First Febrile Urinary Tract Infection), which is not on this map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Topical Steroids to Prevent Recurrent Urinary Tract Infections in Uncircumcised Male Infants With a First Febrile Urinary Tract Infection: a Multi-center Pilot Study
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Summary of best evidence on health education for pediatric urinary tract infections.Frontiers in public health · 2026Pooled it
- Short- versus standard-course antibiotic therapy for urinary tract infection in children: a systematic review and meta-analysis.Pediatric nephrology (Berlin, Germany) · 2025Pooled it
- Article
- Children with recurrent urinary tract infections: who are they and why do we need better prevention options?BMC pediatrics · 2025Article
- Insights into Hospitalized Children with Urinary Tract Infections: Epidemiology and Antimicrobial Resistance Patterns in Israel-A Single Center Study.Children (Basel, Switzerland) · 2024Article
- Article
- Antibiotic resistance in urinary tract infections: A study on trends and contributing factors in outpatient care among Indian patients.Bioinformation · 2024Article
- Urinary Tract Infection and Antimicrobial Resistance Patterns: 5-Year Experience in a Tertiary Pediatric Nephrology Center in the Southwestern Region of Poland.Antibiotics (Basel, Switzerland) · 2023Article
- Effective antimicrobial therapies of urinary tract infections among children in low- and middle-income countries: A systematic review.Pediatric investigation · 2023Review
- Phenotypic and genotypic characteristics ofFrontiers in public health · 2023Article
- Article
- Article
- Emerging Role of Microbiome in the Prevention of Urinary Tract Infections in Children.International journal of molecular sciences · 2022Review
- Changes of urine isolates of Escherichia coli and Klebsiella pneumoniae biofilm affect monocytes' response.World journal of microbiology & biotechnology · 2021Article
- Prospective Study in Children with Complicated Urinary Tract Infection Treated with Autologous Bacterial Lysates.Microorganisms · 2021Article
- Vesicoureteral reflux: we have yet to complete our learning.European journal of pediatrics · 2021Article
- Symptomatology and Clinic of Hydronephrosis Associated With Uretero Pelvic Junction Anomalies.Frontiers in pediatrics · 2020Review
- Renal scarring in children with febrile urinary tract infection.Jornal de pediatriaArticle
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
Abstract
Recurrent urinary tract infection (rUTI) continues to challenge pediatric care providers. The diagnosis of an rUTI can be difficult, especially in young febrile children. Antibiotic resistance rates continue to rise, which limits oral treatment options. Prophylactic antibiotics are used commonly to manage rUTI, but their use increases the risk of rUTI with antibiotic-resistant strains without significantly reducing renal scarring. Alternative therapies for rUTI include probiotics and anthocyanidins (eg, cranberry extract) to reduce gut colonization by uropathogens and prevent bacterial adhesion to uroepithelia, but efficacy data for these treatments are sparse. The future of rUTI care rests in addressing the following contemporary issues: best diagnostic practices, risk factors associated with rUTI, and the prevention of recurrent infection. In this review, we summarize the state of the art for each of these issues and highlight future studies that will aim to take an alternative approach to managing rUTI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.