Evidence map›Paper›PMID 30052174›Full record

ArticleMicrobial genomics2018

Comparative genomics of Salmonella enterica serovar Montevideo reveals lineage-specific gene differences that may influence ecological niche association.

Scott V Nguyen, Dayna M Harhay, James L Bono, Timothy P L Smith, Patricia I Fields, Blake A Dinsmore, Monica Santovenia, Rong Wang, Joseph M Bosilevac, Gregory P Harhay

Abstract read
In one paragraph

Article in Microbial genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Phylogeographic clustering ofApplied and environmental microbiology · 2026
    Article
  3. Article
  4. Longitudinal study highlights patterns ofFrontiers in microbiology · 2025
    Article
  5. Genotypes and associated traits inFrontiers in microbiology · 2025
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  6. Article
  7. mBio · 2024
    Article
  8. Intraspecies competition amongFrontiers in plant science · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. RegionalApplied and environmental microbiology · 2022
    Article
  14. Article
  15. Article
  16. High-Resolution Genomic Comparisons withinApplied and environmental microbiology · 2021
    Article
  17. Phylogeny ofMicrobial genomics · 2021
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Scott V Nguyen1​UCD-Centre for Food Safety, School of Public Health, Physiotherapy and Sports Science, University College Dublin, Belfield, Dublin D04 N2E5, Ireland.
Dayna M Harhay2​USDA-ARS-US Meat Animal Research Center, Clay Center, NE 68933, USA.
James L Bono2​USDA-ARS-US Meat Animal Research Center, Clay Center, NE 68933, USA.
Timothy P L Smith2​USDA-ARS-US Meat Animal Research Center, Clay Center, NE 68933, USA.
Patricia I Fields3​Enteric Disease Laboratory Branch, Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Blake A Dinsmore3​Enteric Disease Laboratory Branch, Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Monica Santovenia3​Enteric Disease Laboratory Branch, Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Rong Wang2​USDA-ARS-US Meat Animal Research Center, Clay Center, NE 68933, USA.
Joseph M Bosilevac2​USDA-ARS-US Meat Animal Research Center, Clay Center, NE 68933, USA.
Gregory P Harhay2​USDA-ARS-US Meat Animal Research Center, Clay Center, NE 68933, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salmonella enterica serovar Montevideo has been linked to recent foodborne illness outbreaks resulting from contamination of products such as fruits, vegetables, seeds and spices. Studies have shown that Montevideo also is frequently associated with healthy cattle and can be isolated from ground beef, yet human salmonellosis outbreaks of Montevideo associated with ground beef contamination are rare. This disparity fuelled our interest in characterizing the genomic differences between Montevideo strains isolated from healthy cattle and beef products, and those isolated from human patients and outbreak sources. To that end, we sequenced 13 Montevideo strains to completion, producing high-quality genome assemblies of isolates from human patients (n=8) or from healthy cattle at slaughter (n=5). Comparative analysis of sequence data from this study and publicly available sequences (n=72) shows that Montevideo falls into four previously established clades, differentially occupied by cattle and human strains. The results of these analyses reveal differences in metabolic islands, environmental adhesion determinants and virulence factors within each clade, and suggest explanations for the infrequent association between bovine isolates and human illnesses.

Indexed as

GenomicsSerogroupAnimalsCattleDisease OutbreaksEcosystemHumansSalmonella entericaSalmonella Food PoisoningSpecies SpecificityUruguayVirulence FactorsVirulence Factorscattlecomparative genomicsCRISPR-CasphylogeneticSalmonella enterica serovar Montevideo

Identifiers

PMID30052174
PMCPMC6159554

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.