Evidence map›Paper›PMID 30051889›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2018

An Experimental Study of Femto-Laser in Assisting Xenograft Acellular Cornea Matrix Lens Transplantation.

Xiaoli Zheng, Dan Zhang, Siyuan Li, Jing Zhang, Juan Zheng, Liqun Du, Jianlu Gao

Open access · hybridAbstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Applications of SMILE-extracted lenticules in ophthalmology.International journal of ophthalmology · 2024
    Review
  2. Review
  3. Corneal xenotransplantation: Where are we standing?Progress in retinal and eye research · 2021
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiaoli ZhengDepartment of Ophthalmology, Liaocheng City People's Hospital, Liaocheng, Shandong, China (mainland).
Dan ZhangDepartment of Ophthalmology, Liaocheng City People's Hospital, Liaocheng, Shandong, China (mainland).
Siyuan LiDepartment of Ophthalmology, Liaocheng City People's Hospital, Liaocheng, Shandong, China (mainland).
Jing ZhangDepartment of Ophthalmology, Liaocheng City People's Hospital, Liaocheng, Shandong, China (mainland).
Juan ZhengDepartment of Joint Laboratory for Translational Medicine Research, Liaocheng City People's Hospital, Liaocheng, Shandong, China (mainland).
Liqun DuDepartment of Ophthalmology, Qilu Hospital of Shandong University, Qilu, Shandong, China (mainland).
Jianlu GaoDepartment of Ophthalmology, Liaocheng City People's Hospital, Liaocheng, Shandong, China (mainland).
Liaocheng People's Hospital · CNQilu Hospital of Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND The aim of this study was to evaluate the feasibility of using a femto-laser in assisting xenograft cornea matrix lens transplantation in correcting ametropia, along with evaluating the effectiveness and predictability of this procedure. MATERIAL AND METHODS A corneal matrix pouch was prepared on the right eyes on 8 healthy New Zealand rabbits by a femto-laser that was also employed to perform small incision lenticule extraction (SMILE) on 8 bovine cornea matrix lenses (+6D). A lens was treated acellular and implanted into a right rabbit cornea matrix pouch. Surface inflammation was observed at 1, 2, 4, 8, 12, and 24 weeks after surgery. Anterior ocular segment optical coherence tomography (OCT), corneal topography, retinoscopy, and cornea endothelial cell enumeration were performed. RESULTS All the surgeries were successfully performed without any complications. The hyperopia condition of the rabbit eyes transformed into myopia status at an early stage and gradually developed hyperopia. Diopter at 24 weeks after surgery was 1/3 of that before surgery. Central corneal thickness stabilized at 4 weeks after surgery. Anterior segment OCT showed a clear lens edge at early post-operative stage, and blurred edge at 24 weeks later, indicating gradual fusion with the rabbit corneal matrix. CONCLUSIONS Femto-laser assisted xenograft corneal matrix lens transplantation is safe and effective in correcting ametropia, with satisfactory predictability, thus providing novel choice for correcting ametropia.

Indexed as

AnimalsCattleCorneaCorneal TopographyCorneal TransplantationFemaleHeterograftsHyperopiaLasers, ExcimerLaser TherapyMaleMyopiaRabbitsRefractive ErrorsRefractive Surgical ProceduresTomography, Optical Coherence

Identifiers

PMID30051889
PMCPMC6076428
OpenAlexW2884330273

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.