Evidence map›Paper›PMID 30051689›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2018

Toxoplasmosis an Overlooked Disease: Seroprevalence in Cancer Patients

Raafat Abdel Malek, Rita Wassef, Enas Rizk, Hoda Sabry, Nevine Tadros, Abdallah Boghdady

Open access · greenAbstract read
In one paragraph

Article in Asian Pacific journal of cancer prevention : APJCP, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Serological and molecular detection ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023
    Article
  7. Article
  8. Evaluation ofMetabolites · 2022
    Article
  9. CanJournal of parasitology research · 2020
    Article
  10. Increased Risk ofBioMed research international · 2020
    Article
  11. Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2019
    Article
  12. Toxoplasmosis in Cancer Patients and Suggestion for ScreeningAsian Pacific journal of cancer prevention : APJCP · 2019
    Article
  13. Validity of a new immunochromatographic test in detection ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Raafat Abdel MalekDepartment of Clinical Oncology, Kasr Al-Ainy Faculty of Medicine, Cairo University, Egypt. Email: Raafat.malek@kasralainy.edu.eg
Rita Wassef
Enas Rizk
Hoda Sabry
Nevine Tadros
Abdallah Boghdady
Cairo University · EGTheodor Bilharz Research Institute · EGHelwan University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Toxoplasmosis is one of the most important cosmopolitan life-threatening diseases in immune-compromised patients. It is caused by an intracellular protozoon: Toxoplasma gondii (T. gondii). The parasite can cause pneumonia, encephalitis or disseminated disease in immune-deficient patients and dangerous congenital anomalies in infants born to mothers infected during early pregnancies. The present study aims to evaluate the prevalence of toxoplasmosis in Egyptian cancer patients and to correlate the prevalence with type of malignancy and the different cancer treatment modalities. Materials and Methods: Blood samples from 150 cancer patients and 50 control subjects have been examined for presence of anti-toxoplasma antibodies using a lateral flow chromatographic immunoassay. Results: Among cancer patients included in this study, the prevalence of anti- T.gondii antibodies was 20% for IgG and 4% for IgM, while in the control group it was 8% and 2% in the same order. This difference was statistically significant for IgG (P =0.003) but not for IgM (P = 0.44). Patients with solid organ tumors treated with chemotherapy had the highest prevalence rate of toxoplasmosis (28%). It was also found higher in males (26%) than females (10%) and higher among urban (18%) than rural dwellers (16%). Conclusion: Cancer patients showed a significantly higher rate of infection with T. gondii than their cross-matched control. For that reason, we recommend the inclusion of a screening test for toxoplasmosis in their routine workup.

Indexed as

Biomarkers, TumorCase-Control StudiesCross-Sectional StudiesEgyptFemaleFollow-Up StudiesHumansImmunoglobulin GImmunoglobulin MMaleNeoplasmsPrevalencePrognosisRisk FactorsSeroepidemiologic StudiesToxoplasmosisBiomarkers, TumorImmunoglobulin GImmunoglobulin MCancerchemotherapyprevalenceradiationToxoplasma gondii.

Identifiers

PMID30051689
PMCPMC6165665
OpenAlexW2891845110

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.