Evidence map›Paper›PMID 30051598›Full record

ArticleESC heart failure2018

Strain imaging to predict response to cardiac resynchronization therapy: a systematic comparison of strain parameters using multiple imaging techniques.

Alwin Zweerink, Wouter M van Everdingen, Robin Nijveldt, Odette A E Salden, Mathias Meine, Alexander H Maass, Kevin Vernooy, Frederik J de Lange, Marc A Vos, Pierre Croisille and 7 more

Abstract readComparative StudyMulticenter Study
In one paragraph

Article in ESC heart failure, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Novel cardiovascular magnetic resonance strain heterogeneity phenotypes predict cardiovascular events: A prospective UK Biobank study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
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  17. Segment length in cine (SLICE) strain analysis: a practical approach to estimate potential benefit from cardiac resynchronization therapy.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
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  18. Article
  19. Efficiency is key.European heart journal. Cardiovascular Imaging · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Alwin ZweerinkDepartment of Cardiology, and Amsterdam Cardiovascular Sciences (ACS), VU University Medical Center, Amsterdam, The Netherlands.
Wouter M van EverdingenDepartment of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Robin NijveldtDepartment of Cardiology, and Amsterdam Cardiovascular Sciences (ACS), VU University Medical Center, Amsterdam, The Netherlands.
Odette A E SaldenDepartment of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Mathias MeineDepartment of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Alexander H MaassDepartment of Cardiology, Thorax Centre, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Kevin VernooyDepartment of Cardiology, Maastricht University Medical Center, Maastricht, The Netherlands.
Frederik J de LangeDepartment of Cardiology, Academic Medical Center, Amsterdam, The Netherlands.
Marc A VosDepartment of Medical Physiology, University of Utrecht, Utrecht, The Netherlands.
Pierre CroisilleUniv Lyon, UJM-Saint-Etienne, INSA, CNRS UMR 5520, INSERM U1206, CREATIS, F-42023, Saint-Etienne, France.
Patrick ClarysseUniv Lyon, UJM-Saint-Etienne, INSA, CNRS UMR 5520, INSERM U1206, CREATIS, F-42023, Saint-Etienne, France.
Bastiaan GeelhoedDepartment of Cardiology, Thorax Centre, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Michiel RienstraDepartment of Cardiology, Thorax Centre, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Isabelle C van GelderDepartment of Cardiology, Thorax Centre, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Albert C van RossumDepartment of Cardiology, and Amsterdam Cardiovascular Sciences (ACS), VU University Medical Center, Amsterdam, The Netherlands.
Maarten J CramerDepartment of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Cornelis P AllaartDepartment of Cardiology, and Amsterdam Cardiovascular Sciences (ACS), VU University Medical Center, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsVarious strain parameters and multiple imaging techniques are presently available including cardiovascular magnetic resonance (CMR) tagging (CMR-TAG), CMR feature tracking (CMR-FT), and speckle tracking echocardiography (STE). This study aims to compare predictive performance of different strain parameters and evaluate results per imaging technique to predict cardiac resynchronization therapy (CRT) response. METHODS AND

resultsTwenty-seven patients were prospectively enrolled and underwent CMR and echocardiographic examination before CRT implantation. Strain analysis was performed in circumferential (CMR-TAG, CMR-FT, and STE-circ) and longitudinal (STE-long) orientations. Regional strain values, parameters of dyssynchrony, and discoordination were calculated. After 12 months, CRT response was measured by the echocardiographic change in left ventricular (LV) end-systolic volume (LVESV). Twenty-six patients completed follow-up; mean LVESV change was -29 ± 27% with 17 (65%) patients showing ≥15% LVESV reduction. Measures of dyssynchrony (SD-TTP

conclusionsEnd-systolic septal strain was the only parameter with a consistent good relation to reverse remodelling after CRT, irrespective of assessment technique. In clinical practice, this measure can be obtained by any available strain imaging technique and provides predictive value on top of current guideline criteria.

Indexed as

AgedCardiac Resynchronization TherapyEchocardiographyFemaleHeart FailureHumansMagnetic Resonance Imaging, CineMaleMiddle AgedMyocardial ContractionPredictive Value of TestsProspective StudiesReproducibility of ResultsVentricular Function, LeftCardiac resynchronization therapy (CRT)Cardiovascular magnetic resonance (CMR)Feature tracking (CMR-FT)Myocardial strain analysisMyocardial tagging (CMR-TAG)Speckle tracking echocardiography (STE)

Identifiers

PMID30051598
PMCPMC6300826

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.