ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2018
Subtle changes in diabetic retinas localised in 3D using OCT.
Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Visual acuity measured with a 3 mm pupil and Maxwellian view for subjective vs. objective focus in patients with exudative retinal disease.Biomedical optics express · 2026Article
- Association and Multimodal Model of Retinal Mid-Peripheral Capillary Free Zones with Structural and Functional Parameters in Diabetic Patients Without Clinical Retinopathy.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Retinal Mid-Peripheral Capillary Free Zones Are Enlarged in Diabetic Patients With No Evidence of Clinical Retinopathy.Translational vision science & technology · 2025Article
- Photoreceptor layer elevation due to subretinal fluid: Impact on visual acuity measurements and simulation from biometrics.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025Article
- Quantifying Putative Retinal Gliosis in Preclinical Alzheimer's Disease.Investigative ophthalmology & visual science · 2024Article
- Retinal mid-peripheral capillary free zones are enlarged in cognitively unimpaired older adults at high risk for Alzheimer's disease.Alzheimer's research & therapy · 2023Article
- Cone Photoreceptors in Diabetic Patients.Frontiers in medicine · 2022Article
- Imaging the Retinal Vasculature.Annual review of vision science · 2021Review
- OCTA reveals remodeling of the peripheral capillary free zones in normal aging.Scientific reports · 2021Article
- Cones in ageing and harsh environments: the neural economy hypothesis.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2020Review
- A recommended "minimum data set" framework for SD-OCT retinal image acquisition and analysis from the Atlas of Retinal Imaging in Alzheimer's Study (ARIAS).Alzheimer's & dementia (Amsterdam, Netherlands) · 2020Article
- Distances From Capillaries to Arterioles or Venules Measured Using OCTA and AOSLO.Investigative ophthalmology & visual science · 2019Article
- The role of ultra-widefield imaging with navigated central and peripheral cross-sectional and three-dimensional swept source optical coherence tomography in ophthalmology: Clinical applications.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
purposeTo detect and localise subtle changes in retinas of diabetic patients who clinically have no diabetic retinopathy (DR) or non-proliferative DR (NPDR) as compared to age- and sex- matched controls. Spectral Domain Optical Coherence Tomography (SD-OCT) and software to examine all retinal layers, including deeper layers, were used to quantify foveal avascular zone size and inner and outer retinal layer thicknesses, as well as to detect axial location of prominent lesions.
methodsDiabetic subjects, 19 total with 16 having no DR and three having non-proliferative retinopathy, were matched with 19 controls with respect to age and sex. Macular-centred SD-OCT grids of 20 × 15° were taken with the Spectralis. En face or transverse images were generated from the SD-OCT data by automatically segmenting all retinal layers. The transverse images were investigated for foveal avascular zone (FAZ) size, retinal vessel calibre, and structural changes. The size of the FAZ was compared for diabetics vs controls using vendor software and manual marking in Photoshop. Inner retinal layer (IRL
resultsThe FAZ area was larger for diabetics (mean ± S.D. = 0.388 ± 0.074 mm
conclusionsOur results demonstrate changes in inner and outer diabetic retinas not readily detectable by clinical exam. IRL
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